Orientador: Neury José Botega

Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas

Resumo: O Estudo de Intervenção Breve Oportuna (EIBO) realizou uma série de ensaios terapêuticos aleatorizados em pacientes internados no Hospital de Clínicas da Unicamp. Objetivo: descrever o perfil clínico e a evolução desses pacientes e decorridos seis meses da alta hospitalar, reavaliar todos os...

Resumo: O Estudo de Intervenção Breve Oportuna (EIBO) realizou uma série de ensaios terapêuticos aleatorizados em pacientes internados no Hospital de Clínicas da Unicamp. Objetivo: descrever o perfil clínico e a evolução desses pacientes e decorridos seis meses da alta hospitalar, reavaliar todos os pacientes por meio de uma entrevista telefônica. Método: Após screening com a Hospital Anxiety and Depression Scale (HAD), os primeiros 50 casos com episódio depressivo confirmados pelo Mini International Neuropsychiatric Interview compuseram a amostra deste estudo da depressão e foram encaminhados para um serviço de saúde pública. Devido ao caráter naturalístico do presente estudo, não interferimos na conduta dos médicos durante a internação. Após 6 meses de alta hospitalar, todos os pacientes foram entrevistados novamente por telefone. Resultados: a média de idade foi 49,3 anos (desvio-padrão:14,5), com predominância do sexo feminino (68%). Infecções, neoplasias malignas, doenças gastrointestinais e renais foram às principais razões de internação, muitas vezes associadas a doenças de base (principalmente hipertensão arterial, diabetes e cardiopatias). Decorridos seis meses da alta, cinco pacientes faleceram, seis não puderam ser contatados e um recusou a nova entrevista. Dos 38 reavaliados, dois terços continuavam deprimidos. Apenas 12 pacientes foram tratados e desses 7 (58%) foram com antidepressivos. Continuar deprimido associou-se à ideação suicida e a reinternações. Banalização dos sintomas depressivos, medo de ficar dependente de psicofármacos e descrédito em antidepressivos e psicoterapias constituíram barreiras para que 21 pacientes (55%) não buscassem tratamento para depressão. Dos 17 que o fizeram, 5 não conseguiram tratamento. Conclusão: Este estudo inédito demonstrou que após seis meses da alta hospitalar, 66% dos pacientes continuam deprimidos e 15% recebem tratamento. E dos que continuam deprimidos 64% apresentam ideação suicida e 16% tiveram novas internações. As crenças que os pacientes têm sobre depressão e o tratamento também constituem fatores de impedimentos subjetivos para buscar tratamento

Abstract: The Study of Brief Opportunity Intervention (EIBO) performed a series of randomized clinical trials with patients admitted to Clinical Hospital of the State University of Campinas (Unicamp-Brazil). Objective: to describe both the clinical profile and evolution from the subjects, after...

Abstract: The Study of Brief Opportunity Intervention (EIBO) performed a series of randomized clinical trials with patients admitted to Clinical Hospital of the State University of Campinas (Unicamp-Brazil). Objective: to describe both the clinical profile and evolution from the subjects, after 6-month discharge period and also to review ali the patients through a telephone call interview. Methodology: As part of this research project, the researchers screened ali patients using of Hospital Anxiety and Depression Scale (HAD). As part of this research project, the researchers screened ali patients using of Hospital Anxiety and Depression Scale (HAD). The first fifty (50) cases of depressive episode confirmed through Mini International Neuropsychiatric Interview (MINI) received standardized information about depression and were referred to a public health service to start the treatment. Due to the naturalistic nature of the present study, there was no interference on the assistant doctors' treatment provided to patients during hospitalization. After six-months of hospital discharge, ali the patients were reassessed through a telephone interview. Results: Patients' mean age was 49.3 years old (standard deviation: 14.5), being 68% females. Infections, malign neoplasias, renal and gastrointestinal diseases were the major reasons for hospitalization and they were many times associated with underlying diseases (mainly high blood pressure, diabetes and heart diseases). After six-month of discharge, five patients died, six could not be contacted by telephone and one of them refused to participate on a new interview. Out of 38 reassessed patients, two-thirds continued depressed. At the baseline assessment, this was the group that reported more frequently pain and suicidal behavior. Only one-third of the patients had received treatment for depression (from these 12 treated patients, 7 (58%) received antidepressive medication). Maintained depression was associated with suicidal ideation and rehospitalization. The discredit on depressive symptoms, the fear of becoming dependent on psychopharmacological medication and the disbelief on antidepressive drugs and psychotherapies were barriers that led 21 patients not to search treatment for depression. Out of 17 who search for treatment at public healthcare services, 5 could not get it. Although the patients were assessed by several physicians, only one out of three patients received some treatment for depression; only one, out of five, received an antidepressive medication. Conclusion: The findings show that after 6-month discharge period, 66% patients remained depressed and only 15% of them received treatment. The patients who continued depressed, they 64% showed suicidal ideation and 16% were rehospitalized. The beliefs that the patients have about depression and its treatment also constitute factors that impede them of looking for treatment