Agradecimentos: The authors thank Coordination for the Improvement of Higher Education Personnel (CAPES). The authors would like to thank the Multiuser Core Laboratory of Biological Analysis and Molecular Biology (BioMol) at Universidade Tecnológica Federal do Paraná (UTFPR), Câmpus Dois Vizinhos for the performed analysis. The access to databases was funded by the Brazilian government - Coordination for the Improvement of Higher Education Personnel (CAPES) Ver menos

Abstract: Acephate is a pesticide classified as moderately toxic, and its metabolite methamidophos is highly toxic for mammals and birds; even so, it is one of the most used insecticides in pest control for agricultural and domestic use. Acephate toxicity affects both target and non-target organisms and causes serious damage to the environment. There are several studies on different perspectives of acephate, such as monitoring, toxicity, and modeling. In this sense, this research aims to identify the structure of intellectual production on acephate and analyze the gaps and trends of scientific production on acephate through a scientometric analysis. The data was obtained from the Web of Science database, and after the refinement, 1.085 documents were used. A temporal pattern of the main research objectives is displayed. Most selected studies evaluated acephate efficiency, followed by toxicity and residue detection methods. The USA, China, India, Brazil, and Japan had the highest number of publications on acephate. The keywords most utilized were pesticides, toxicity, insecticide resistance, and residue. Research involving acephate requires greater attention from areas such as ecotoxicology, biochemistry, genetics, and biotechnology. There needed to be more discussions on chronic toxicity, genotoxicity, and cytotoxicity. Moreover, few studies about metabolic and biochemical pathways and genes related to acephate action and biodegradation were scarce Ver menos