Design and synthesis of N‐Acylated aza‐goniothalamin derivatives and evaluation of their in vitro and in vivo antitumor activity
ARTIGO
Inglês
Agradecimentos: The authors thank the São Paulo Research Foundation—FAPESP (grants 2009/51602‐5, 2012/18281‐3, and 2010/16990‐1), CNPq, and Capes for financial support, and the National Cancer Institute (Frederick, MD, USA) for granting the human tumor cell lines. We als
Herein we describe the synthesis of a focused library of compounds based on the structure of goniothalamin (1 ) and the evaluation of the potential antitumor activity of the compounds. N‐Acylation of aza‐goniothalamin (2 ) restored the in vitro antiprolif
FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP
2009/51602‐5; 2012/18281‐3; 2010/16990‐1
COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPES
CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ
Fechado
Design and synthesis of N‐Acylated aza‐goniothalamin derivatives and evaluation of their in vitro and in vivo antitumor activity
Design and synthesis of N‐Acylated aza‐goniothalamin derivatives and evaluation of their in vitro and in vivo antitumor activity
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Chemmedchem: chemistry enabling drug discovery (Fonte avulsa) |