Reduced collagen accumulation and augmented MMP-2 activity in left ventricle of old rats submitted to high-intensity resistance training

Reduced collagen accumulation and augmented MMP-2 activity in left ventricle of old rats submitted to high-intensity resistance training

Vinicius Guzzoni, Rita de Cassia Marqueti, Joao Luiz Quagliotti Durigan, Hernandes Faustino de Carvalho, Rafael Luis Bressani Lino, Marcelo S. Mekaro, Tayna Oliveira Costa Santos, Andre Souza Mecawi, Jose Antunes Rodrigues, Jeffrey Hord

ARTIGO

Inglês

Agradecimentos: We thank Dr. James M. Kuczmarski for kindly providing invaluable advice and feedback in the writing of this manuscript

Progressive fibrosis is a hallmark of the aging heart. Age-related fibrosis is modulated by endurance exercise training ; however, little is known concerning the influence of resistance training (RT). Therefore we investigated the chronic effects of high-

CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ

465699/2014-6

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP

2013/00798-2; 2014/50938-8

COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPES

88887.136367/2017-00

fechado

Coração - Envelhecimento
Coração - Ventriculo esquerdo
Fibrose
Colágeno
Metaloproteinase 2 da matriz
Artigo de pesquisa

DOI:

Texto completo:

Reduced collagen accumulation and augmented MMP-2 activity in left ventricle of old rats submitted to high-intensity resistance training

Vinicius Guzzoni, Rita de Cassia Marqueti, Joao Luiz Quagliotti Durigan, Hernandes Faustino de Carvalho, Rafael Luis Bressani Lino, Marcelo S. Mekaro, Tayna Oliveira Costa Santos, Andre Souza Mecawi, Jose Antunes Rodrigues, Jeffrey Hord 

										

											
											
										

									

									

										

											

												
Reduced collagen accumulation and augmented MMP-2 activity in left ventricle of old rats submitted to high-intensity resistance training

											

												

														

		

							

					Vinicius Guzzoni, Rita de Cassia Marqueti, Joao Luiz Quagliotti Durigan, Hernandes Faustino de Carvalho, Rafael Luis Bressani Lino, Marcelo S. Mekaro, Tayna Oliveira Costa Santos, Andre Souza Mecawi, Jose Antunes Rodrigues, Jeffrey Hord
				

		

	


												

										

										
    
										
    
											
										
    
									
    
								
    
							
    
						
    
					
    
				
    
			
    
		
    
	
    

    

	

		
    
			
    
				
    
					
    
								
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Journal of applied physiology												
    
											
    
											
    
												
    
											
    
											
    
												
    Vol. 123, no. 3 (Sept., 2017), p. 655-663