Dectin-1 activation exacerbates obesity and insulin resistance in the absence of MyD88

Dectin-1 activation exacerbates obesity and insulin resistance in the absence of MyD88

Angela Castoldi, Vinicius Andrade-Oliveira, Cristhiane Favero Aguiar, Mariane Tami Amano, Jennifer Lee, Marcelli Terumi Miyagi, Marcela Teatin Latancia, Tarcio Teodoro Braga, Marina Burgos da Silva, Aline Ignacio, Carola Correia Lima

ARTIGO

Inglês

Agradecimentos: This work was supported by Fundação de Amparo a Pesquisa do Estado de São Paulo (FAPESP, grant numbers 11/15682-4, 12/02270-2, and 15/18121-4) and Conselho Nacional de Desenvolvimento Cientı´fico e Tecnológico (CNPq, Regenera INCT Process grant 465656/201

The underlying mechanism by which MyD88 regulates the development of obesity, metainflammation, and insulin resistance (IR) remains unknown. Global deletion of MyD88 in high-fat diet (HFD)fed mice resulted in increased weight gain, impaired glucose homeos

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP

CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ

aberto

Dectin-1 activation exacerbates obesity and insulin resistance in the absence of MyD88

Angela Castoldi, Vinicius Andrade-Oliveira, Cristhiane Favero Aguiar, Mariane Tami Amano, Jennifer Lee, Marcelli Terumi Miyagi, Marcela Teatin Latancia, Tarcio Teodoro Braga, Marina Burgos da Silva, Aline Ignacio, Carola Correia Lima


										

Dectin-1 activation exacerbates obesity and insulin resistance in the absence of MyD88

Angela Castoldi, Vinicius Andrade-Oliveira, Cristhiane Favero Aguiar, Mariane Tami Amano, Jennifer Lee, Marcelli Terumi Miyagi, Marcela Teatin Latancia, Tarcio Teodoro Braga, Marina Burgos da Silva, Aline Ignacio, Carola Correia Lima

    Fontes

    Cell reports

    Vol. 19, no. 11 (June, 2017), p. 2272-2288