Peptide R18H from BRN2 transcription factor POU domain displays antitumor activity in vitro and in vivo and induces apoptosis in B16F10-Nex2 cells

Peptide R18H from BRN2 transcription factor POU domain displays antitumor activity in vitro and in vivo and induces apoptosis in B16F10-Nex2 cells

Fernanda F.M. da Cunha, Katia C.U. Mugnol, Filipe M. de Melo, Marta V.S.Q. Nascimento, Ricardo A. de Azevedo, Raquel T.S. Santos, Jéssica A. Magalhães, Danilo C. Miguel, Dayane B. Tada, Renato A. Mortara, Luiz R. Travassos, D Arruda

ARTIGO

Inglês

Agradecimentos: We thank Prof. Dr. Edgar J. P. Gamero from Federal University of Mato Grosso do Sul for the nontumor J774 1.6, Prof. Dr. Júlio Scharfstein from Federal University of Rio de Janeiro for the nontumor HUVEC and Prof. Dr. Luis F. Lima Reis, Hospital Sirio Li

BRN2 transcription factor is associated with the development of malignant melanoma. The cytotoxic activities and cell death mechanism against B16F10-Nex2 cells were determined with synthetic peptide R18H derived from the POU domain of the BRN2 transcripti

CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP

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Peptide R18H from BRN2 transcription factor POU domain displays antitumor activity in vitro and in vivo and induces apoptosis in B16F10-Nex2 cells

Fernanda F.M. da Cunha, Katia C.U. Mugnol, Filipe M. de Melo, Marta V.S.Q. Nascimento, Ricardo A. de Azevedo, Raquel T.S. Santos, Jéssica A. Magalhães, Danilo C. Miguel, Dayane B. Tada, Renato A. Mortara, Luiz R. Travassos, D Arruda


										

Peptide R18H from BRN2 transcription factor POU domain displays antitumor activity in vitro and in vivo and induces apoptosis in B16F10-Nex2 cells

Fernanda F.M. da Cunha, Katia C.U. Mugnol, Filipe M. de Melo, Marta V.S.Q. Nascimento, Ricardo A. de Azevedo, Raquel T.S. Santos, Jéssica A. Magalhães, Danilo C. Miguel, Dayane B. Tada, Renato A. Mortara, Luiz R. Travassos, D Arruda

    Fontes

    Anti-cancer agents in medicinal chemistry

    supl 3, no. 19 (2019), p. 389-401