Pancreatic alpha-cell dysfunction contributes to the disruption of glucose homeostasis and compensatory insulin hypersecretion in glucocorticoid-treated rats

Pancreatic alpha-cell dysfunction contributes to the disruption of glucose homeostasis and compensatory insulin hypersecretion in glucocorticoid-treated rats

Alex Rafacho, Luiz M. Gonçalves-Neto, Junia C. Santos-Silva, Paloma Alonso-Magdalena, Beatriz Merino, Sebastião R. Taboga, Everardo M. Carneiro, Antonio C. Boschero, Angel Nadal, Ivan Quesada

ARTIGO

Inglês

Glucocorticoid (GC)-based therapies can cause insulin resistance (IR), glucose intolerance, hyperglycemia and, occasionally, overt diabetes. Understanding the mechanisms behind these metabolic disorders could improve the management of glucose homeostasis

CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP

Aberto

Pancreatic alpha-cell dysfunction contributes to the disruption of glucose homeostasis and compensatory insulin hypersecretion in glucocorticoid-treated rats

Alex Rafacho, Luiz M. Gonçalves-Neto, Junia C. Santos-Silva, Paloma Alonso-Magdalena, Beatriz Merino, Sebastião R. Taboga, Everardo M. Carneiro, Antonio C. Boschero, Angel Nadal, Ivan Quesada


										

Pancreatic alpha-cell dysfunction contributes to the disruption of glucose homeostasis and compensatory insulin hypersecretion in glucocorticoid-treated rats

Alex Rafacho, Luiz M. Gonçalves-Neto, Junia C. Santos-Silva, Paloma Alonso-Magdalena, Beatriz Merino, Sebastião R. Taboga, Everardo M. Carneiro, Antonio C. Boschero, Angel Nadal, Ivan Quesada

    Fontes

    PLoS one

    Vol. 9, no. 4 (Apr., 2014), p. 1-11, n. art. e93531