Ethidium bromide-induced demyelination of the sciatic nerve of adult Wistar rats

Ethidium bromide-induced demyelination of the sciatic nerve of adult Wistar rats

G. Riet-Correa, C.G. Fernandes, L.A.V. Pereira, D.L. Graça

ARTIGO

Inglês

Peripheral nerve ultrastructure was assessed after single or multiple local injections of the intercalating dye ethidium bromide. Thirty-four adult Wistar rats of both sexes were divided into five groups and maintained in a controlled environment with rat chow and water ad libitum throughout the...

for groups 2, 3, 4 and 5, all rats were killed 10 days after the last injection and the lesions were investigated by light and transmission electron microscopy. In the acute lesions, intoxicated Schwann cells showed a vacuolated cytoplasm and separation of the sheaths from the axon. Myelin sheaths...

Peripheral nerve ultrastructure was assessed after single or multiple local injections of the intercalating dye ethidium bromide. Thirty-four adult Wistar rats of both sexes were divided into five groups and maintained in a controlled environment with rat chow and water ad libitum throughout the...

CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DO RIO GRANDE DO SUL - FAPERGS

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP

Aberto

Ethidium bromide-induced demyelination of the sciatic nerve of adult Wistar rats

G. Riet-Correa, C.G. Fernandes, L.A.V. Pereira, D.L. Graça


										

Ethidium bromide-induced demyelination of the sciatic nerve of adult Wistar rats

G. Riet-Correa, C.G. Fernandes, L.A.V. Pereira, D.L. Graça

    Fontes

    Brazilian journal of medical and biological research

    Vol. 35, no. 1 (Jan., 2002), p. 99-104