The preclinical discovery and development of oral miltefosine for the treatment of visceral leishmaniasis : a case history

The preclinical discovery and development of oral miltefosine for the treatment of visceral leishmaniasis : a case history

Juliana Q. Reimao, Debora P. Pita Pedro, Adriano C. Coelho

ARTIGO

Inglês

Agradecimentos: Institutional Scientific Initiation Scholarship Program from Faculdade de Medicina de Jundiai (PIBIC/FMJ); UK Research and Innovation via the Global Challenges Research Fund under grant 'A Global Network for Neglected Tropical Diseases'

Introduction: Visceral leishmaniasis (VL) is a vector-borne disease caused by Leishmania donovani or Leishmania infantum. Closely related to poverty, VL is fatal and represents one of the main burdens on public health in developing countries. Treatment of VL relies exclusively on chemotherapy, a...

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The preclinical discovery and development of oral miltefosine for the treatment of visceral leishmaniasis : a case history

Juliana Q. Reimao, Debora P. Pita Pedro, Adriano C. Coelho


										

The preclinical discovery and development of oral miltefosine for the treatment of visceral leishmaniasis : a case history

Juliana Q. Reimao, Debora P. Pita Pedro, Adriano C. Coelho

    Fontes

    Expert Opinion on Drug Discovery

    Vol. 15, no. 6 (June, 2020), p. 647-658