Quantitative proteomic analysis reveals metabolic alterations, calcium dysregulation, and increased expression of extracellular matrix proteins in Laminin α2 Chain-deficient muscle

Quantitative proteomic analysis reveals metabolic alterations, calcium dysregulation, and increased expression of extracellular matrix proteins in Laminin α2 Chain-deficient muscle

Bruno Menezes de Oliveira, Cintia Y. Matsumura, Cibely C. Fontes-Oliveira, Kinga I. Gawlik, Helena Acosta, Patrik Wernhoff, Madeleine Durbeej

ARTIGO

Inglês

Congenital muscular dystrophy with laminin α2 chain deficiency (MDC1A) is one of the most severe forms of muscular disease and is characterized by severe muscle weakness and delayed motor milestones. The genetic basis of MDC1A is well known, yet the secondary mechanisms ultimately leading to muscle...

COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPES

Fechado

Quantitative proteomic analysis reveals metabolic alterations, calcium dysregulation, and increased expression of extracellular matrix proteins in Laminin α2 Chain-deficient muscle

Bruno Menezes de Oliveira, Cintia Y. Matsumura, Cibely C. Fontes-Oliveira, Kinga I. Gawlik, Helena Acosta, Patrik Wernhoff, Madeleine Durbeej


										

Quantitative proteomic analysis reveals metabolic alterations, calcium dysregulation, and increased expression of extracellular matrix proteins in Laminin α2 Chain-deficient muscle

Bruno Menezes de Oliveira, Cintia Y. Matsumura, Cibely C. Fontes-Oliveira, Kinga I. Gawlik, Helena Acosta, Patrik Wernhoff, Madeleine Durbeej

    Fontes

    Molecular and cellular proteomics

    Vol. 13, no. 11 (2014), p. 3001-3013