In vitro evaluation of permeation, toxicity and effect of praziquantel-loaded solid lipid nanoparticles against Schistosoma mansoni as a strategy to improve efficacy of the schistosomiasis treatment

In vitro evaluation of permeation, toxicity and effect of praziquantel-loaded solid lipid nanoparticles against Schistosoma mansoni as a strategy to improve efficacy of the schistosomiasis treatment

A. L. R. de Souza, E. B. Souto, M. V. Chaud, R. N. de Oliveira, T. Andreani, S. M. Allegretti, C. P. Kiill, F. K. dos Santos, A. M. Silva, M. P. D. Gremiao

ARTIGO

Inglês

Agradecimentos: European Union (EU)

Solid lipid nanoparticles (SLN) are a promising drug delivery system for oral administration of poorlywater soluble drugs because of their capacity to increase the solubility of drug molecules when loaded in their lipid matrices, with the resulting improvement of the drug bioavailability. In the...

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP

CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ

COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPES

Fechado

In vitro evaluation of permeation, toxicity and effect of praziquantel-loaded solid lipid nanoparticles against Schistosoma mansoni as a strategy to improve efficacy of the schistosomiasis treatment

A. L. R. de Souza, E. B. Souto, M. V. Chaud, R. N. de Oliveira, T. Andreani, S. M. Allegretti, C. P. Kiill, F. K. dos Santos, A. M. Silva, M. P. D. Gremiao


										

In vitro evaluation of permeation, toxicity and effect of praziquantel-loaded solid lipid nanoparticles against Schistosoma mansoni as a strategy to improve efficacy of the schistosomiasis treatment

A. L. R. de Souza, E. B. Souto, M. V. Chaud, R. N. de Oliveira, T. Andreani, S. M. Allegretti, C. P. Kiill, F. K. dos Santos, A. M. Silva, M. P. D. Gremiao

    Fontes

    International journal of pharmaceutics

    Vol. 463, no. 1 (Mar., 2014), p. 31-37