Glucocorticoids in vivo induce both insulin hypersecretion and enhanced glucose sensitivity of stimulus-secretion coupling in isolated rat islets

Glucocorticoids in vivo induce both insulin hypersecretion and enhanced glucose sensitivity of stimulus-secretion coupling in isolated rat islets

Alex Rafacho, Laura Marroquí, Sebastião R. Taboga, Júlia L. F. Abrantes, Leonardo R. Silveira, Antonio C. Boschero, Everardo M. Carneiro, José R. Bosqueiro, Angel Nadal, Ivan Quesada

ARTIGO

Inglês

Although glucocorticoids are widely used as antiinflammatory agents in clinical therapies, they may cause serious side effects that include insulin resistance and hyperinsulinemia. To study the potential functional adaptations of the islet of Langerhans to in vivo glucocorticoid treatment, adult...

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP

Fechado

Glucocorticoids in vivo induce both insulin hypersecretion and enhanced glucose sensitivity of stimulus-secretion coupling in isolated rat islets

Alex Rafacho, Laura Marroquí, Sebastião R. Taboga, Júlia L. F. Abrantes, Leonardo R. Silveira, Antonio C. Boschero, Everardo M. Carneiro, José R. Bosqueiro, Angel Nadal, Ivan Quesada


										

Glucocorticoids in vivo induce both insulin hypersecretion and enhanced glucose sensitivity of stimulus-secretion coupling in isolated rat islets

Alex Rafacho, Laura Marroquí, Sebastião R. Taboga, Júlia L. F. Abrantes, Leonardo R. Silveira, Antonio C. Boschero, Everardo M. Carneiro, José R. Bosqueiro, Angel Nadal, Ivan Quesada

    Fontes

    Endocrinology

    Vol. 151, no. 1 (Jan., 2010), p. 85-95