S-nitroso-N-acetylcysteine (SNAC) prevents myocardial alterations in hypercholesterolemic LDL receptor knockout mice by antiinflammatory action

S-nitroso-N-acetylcysteine (SNAC) prevents myocardial alterations in hypercholesterolemic LDL receptor knockout mice by antiinflammatory action

Jose Antonio D. Garcia, Leandro dos Santos, Andre L. Moura, Kelly Fabiane S. Ricardo, Amarylis Claudine B. A. Wanschel, Silvia M. Shishido, Regina C. Spadari-Bratfisch, Heraldo P. de Souza, Marta H. Krieger

ARTIGO

Inglês

We investigated the ability of S-nitroso-N-acetylcyseine (SNAC) to prevent structural and functional myocardial alterations in hypercholesterolemic mice. C57BL6 wild-type (WT) and LDL-R-/male mice (S) were fed a standard diet for 15 days. LDL-R-/- mice (S) showed an 11% increase in blood pressure,...

Fechado

S-nitroso-N-acetylcysteine (SNAC) prevents myocardial alterations in hypercholesterolemic LDL receptor knockout mice by antiinflammatory action

Jose Antonio D. Garcia, Leandro dos Santos, Andre L. Moura, Kelly Fabiane S. Ricardo, Amarylis Claudine B. A. Wanschel, Silvia M. Shishido, Regina C. Spadari-Bratfisch, Heraldo P. de Souza, Marta H. Krieger


										

S-nitroso-N-acetylcysteine (SNAC) prevents myocardial alterations in hypercholesterolemic LDL receptor knockout mice by antiinflammatory action

Jose Antonio D. Garcia, Leandro dos Santos, Andre L. Moura, Kelly Fabiane S. Ricardo, Amarylis Claudine B. A. Wanschel, Silvia M. Shishido, Regina C. Spadari-Bratfisch, Heraldo P. de Souza, Marta H. Krieger

    Fontes

    Journal of cardiovascular pharmacology

    Vol. 51, no. 1 (Jan., 2008), p. 78-85