High doses of dexamethasone induce increased β-cell proliferation in pancreatic rat islets

High doses of dexamethasone induce increased β-cell proliferation in pancreatic rat islets

Alex Rafacho, Tânia M. Cestari, Sebastião R. Taboga, Antonio C. Boschero, José R. Bosqueiro

ARTIGO

Inglês

Activation of insulin signaling and cell cycle intermediates is required for adult β-cell proliferation. Here, we report a model to study β-cell proliferation in living rats by administering three different doses of dexamethasone (0.1, 0.5, and 1.0 mg/kg ip, DEX 0.1, DEX 0.5, and DEX 1.0,...

CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP

Fechado

High doses of dexamethasone induce increased β-cell proliferation in pancreatic rat islets

Alex Rafacho, Tânia M. Cestari, Sebastião R. Taboga, Antonio C. Boschero, José R. Bosqueiro


										

High doses of dexamethasone induce increased β-cell proliferation in pancreatic rat islets

Alex Rafacho, Tânia M. Cestari, Sebastião R. Taboga, Antonio C. Boschero, José R. Bosqueiro

    Fontes

    American journal of physiology: endocrinology and metabolism

    Vol. 296, no. 4 (Apr., 2009), p. E681-E689