Pancreatic islets from dexamethasone-treated rats show alterations in global gene expression and mitochondrial pathways

Pancreatic islets from dexamethasone-treated rats show alterations in global gene expression and mitochondrial pathways

Leticia P. Roma, Kleber L. A. Souza, Everardo M. Carneiro, Antonio C. Boschero, Jose R. Bosqueiro

ARTIGO

Inglês

Chronic administration of glucocorticoids (GC) leads to characteristic features of type 2 diabetes in mammals. The main action of dexamethasone in target cells occurs through modulation of gene expression, although the exact mechanisms are still unknown. We therefore investigated the gene expression...

CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP

Fechado

Pancreatic islets from dexamethasone-treated rats show alterations in global gene expression and mitochondrial pathways

Leticia P. Roma, Kleber L. A. Souza, Everardo M. Carneiro, Antonio C. Boschero, Jose R. Bosqueiro


										

Pancreatic islets from dexamethasone-treated rats show alterations in global gene expression and mitochondrial pathways

Leticia P. Roma, Kleber L. A. Souza, Everardo M. Carneiro, Antonio C. Boschero, Jose R. Bosqueiro

    Fontes

    General physiology and biophysics

    Vol. 31, no. 1 (Mar., 2012), p. 65-76