Knocking down low molecular weight protein tyrosine phosphatase (LMW-PTP) reverts chemoresistance through inactivation of Src and Bcr-Abl proteins

Knocking down low molecular weight protein tyrosine phosphatase (LMW-PTP) reverts chemoresistance through inactivation of Src and Bcr-Abl proteins

Paula A. Ferreira, Roberta R. Ruela-de-Sousa, Karla C. S. Queiroz, Ana Carolina S. Souza, Renato Milani, Ronaldo Aloise Pilli, Maikel P. Peppelenbosch, Jeroen den Hertog, Carmen V. Ferreira

ARTIGO

Inglês

The development of multidrug resistance (MDR) limits the efficacy of continuous chemotherapeutic treatment in chronic myelogenous leukemia (CML). Low molecular weight protein tyrosine phosphatase (LMW-PTP) is up-regulated in several cancers and has been associated to poor prognosis. This prompted us...

CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP

Aberto

Knocking down low molecular weight protein tyrosine phosphatase (LMW-PTP) reverts chemoresistance through inactivation of Src and Bcr-Abl proteins

Paula A. Ferreira, Roberta R. Ruela-de-Sousa, Karla C. S. Queiroz, Ana Carolina S. Souza, Renato Milani, Ronaldo Aloise Pilli, Maikel P. Peppelenbosch, Jeroen den Hertog, Carmen V. Ferreira


										

Knocking down low molecular weight protein tyrosine phosphatase (LMW-PTP) reverts chemoresistance through inactivation of Src and Bcr-Abl proteins

Paula A. Ferreira, Roberta R. Ruela-de-Sousa, Karla C. S. Queiroz, Ana Carolina S. Souza, Renato Milani, Ronaldo Aloise Pilli, Maikel P. Peppelenbosch, Jeroen den Hertog, Carmen V. Ferreira

    Fontes

    PLoS one

    Vol. 7, no. 9 (Sep., 2012), n. art. e44312