Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats : involvement of serum‐ and glucocorticoid‐regulated kinase type 1

Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats : involvement of serum‐ and glucocorticoid‐regulated kinase type 1

Beatriz Martin-Fernandez, Natalia de las Heras, Maria Miana, Sandra Ballesteros, Maria Valero-Munoz, Dalton Vassallo, Ana Paula Davel, Luciana Venturini Rossoni, Victoria Cachofeiro, Vicente Lahera

ARTIGO

Inglês

Persistent beta-adrenergic receptor stimulation with isoproterenol is associated with cardiac hypertrophy as well as cardiac synthesis of angiotensin II. Serum- and glucocorticoid-regulated kinase type 1 (SGK-1) is a key mediator in structural, functional and molecular cardiac effects of aldosterone...

Fechado

Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats : involvement of serum‐ and glucocorticoid‐regulated kinase type 1

Beatriz Martin-Fernandez, Natalia de las Heras, Maria Miana, Sandra Ballesteros, Maria Valero-Munoz, Dalton Vassallo, Ana Paula Davel, Luciana Venturini Rossoni, Victoria Cachofeiro, Vicente Lahera


										

Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats : involvement of serum‐ and glucocorticoid‐regulated kinase type 1

Beatriz Martin-Fernandez, Natalia de las Heras, Maria Miana, Sandra Ballesteros, Maria Valero-Munoz, Dalton Vassallo, Ana Paula Davel, Luciana Venturini Rossoni, Victoria Cachofeiro, Vicente Lahera

    Fontes

    Experimental physiology

    Vol. 97, no. 6 (June, 2012), p. 710-718