The exocyst is required for trypanosome invasion and the repair of mechanical plasma membrane wounds

The exocyst is required for trypanosome invasion and the repair of mechanical plasma membrane wounds

Maria Cecilia Fernandes, Matthias Corrotte, Danilo C. Miguel, Christina Tam, Norma W. Andrews

ARTIGO

Inglês

Agradecimentos: We thank Dr D. Toomre (Yale University) for the VSVG construct, Dr W. Guo (University of Pennsylvania) for antibodies and A. Beaven and K. Class (University of Maryland) for assistance with confocal microscopy and flow cytometry, respectively

The process of host cell invasion by Trypanosoma cruzi shares mechanistic elements with plasma membrane injury and repair. Both processes require Ca2+-triggered exocytosis of lysosomes, exocytosis of acid sphingomyelinase and formation of ceramide-enriche

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The exocyst is required for trypanosome invasion and the repair of mechanical plasma membrane wounds

Maria Cecilia Fernandes, Matthias Corrotte, Danilo C. Miguel, Christina Tam, Norma W. Andrews


										

The exocyst is required for trypanosome invasion and the repair of mechanical plasma membrane wounds

Maria Cecilia Fernandes, Matthias Corrotte, Danilo C. Miguel, Christina Tam, Norma W. Andrews

    Fontes

    Journal of Cell Science

    Vol. 128, no. 1 (2015), p. 27-32