The exocyst is required for trypanosome invasion and the repair of mechanical plasma membrane wounds
ARTIGO
Inglês
Agradecimentos: We thank Dr D. Toomre (Yale University) for the VSVG construct, Dr W. Guo (University of Pennsylvania) for antibodies and A. Beaven and K. Class (University of Maryland) for assistance with confocal microscopy and flow cytometry, respectively
The process of host cell invasion by Trypanosoma cruzi shares mechanistic elements with plasma membrane injury and repair. Both processes require Ca2+-triggered exocytosis of lysosomes, exocytosis of acid sphingomyelinase and formation of ceramide-enriche
fechado
DOI: https://doi.org/10.1242/jcs.150573
Texto completo: https://jcs.biologists.org/content/128/1/27.short
The exocyst is required for trypanosome invasion and the repair of mechanical plasma membrane wounds
The exocyst is required for trypanosome invasion and the repair of mechanical plasma membrane wounds
Fontes
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Journal of Cell Science Vol. 128, no. 1 (2015), p. 27-32 |