A new heparan sulfate from the mollusk nodipecten nodosus inhibits merozoite invasion and disrupts rosetting and cytoadherence of plasmodium falciparum

A new heparan sulfate from the mollusk nodipecten nodosus inhibits merozoite invasion and disrupts rosetting and cytoadherence of plasmodium falciparum

M.F. Bastos, L. Albrecht, A.M. Gomes, S.C.P. Lopes, C.P. Vicente, R.P.M. de Almeida, G.C. Cassiano, R.J.C. Fonseca, C.C. Werneck, M.S.G. Pavão, F.T.M. Costa

ARTIGO

Inglês

Despite treatment with effective antimalarial drugs, the mortality rate is still high in severe cases of the disease, highlighting the need to find adjunct therapies that can inhibit the adhesion of Pf-iEs. In this context, we evaluated a new heparan sulfate (HS) from Nodipecten nodosus for...

CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ

FUNDAÇÃO CARLOS CHAGAS FILHO DE AMPARO À PESQUISA DO ESTADO DO RIO DE JANEIRO - FAPERJ

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP

Aberto

A new heparan sulfate from the mollusk nodipecten nodosus inhibits merozoite invasion and disrupts rosetting and cytoadherence of plasmodium falciparum

M.F. Bastos, L. Albrecht, A.M. Gomes, S.C.P. Lopes, C.P. Vicente, R.P.M. de Almeida, G.C. Cassiano, R.J.C. Fonseca, C.C. Werneck, M.S.G. Pavão, F.T.M. Costa


										

A new heparan sulfate from the mollusk nodipecten nodosus inhibits merozoite invasion and disrupts rosetting and cytoadherence of plasmodium falciparum

M.F. Bastos, L. Albrecht, A.M. Gomes, S.C.P. Lopes, C.P. Vicente, R.P.M. de Almeida, G.C. Cassiano, R.J.C. Fonseca, C.C. Werneck, M.S.G. Pavão, F.T.M. Costa

    Fontes

    Memórias do Instituto Oswaldo Cruz

    Vol. 114 (2019), n. art. e190088