Essential role of the PGC‐1α/PPARβ axis in Ucp3 gene induction

Essential role of the PGC‐1α/PPARβ axis in Ucp3 gene induction

Tanes I. Lima, Dimitrius Guimaraes, Carlos H. Sponton, Marcio C. Bajgelman, Soledad Palameta, Jessica M. Toscaro, Osvaldo Reis, Leonardo R. Silveira

ARTIGO

Inglês

We report that the peroxisome proliferator-activated receptor (PPAR)gamma coactivator 1-alpha (PGC-1 alpha)/PPAR beta axis is a crucial mediator of uncoupling protein 3 (UCP3) expression in skeletal muscle cells via the transactivativation of a distal PPAR response element at the Ucp3 gene promoter....

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Fechado

Essential role of the PGC‐1α/PPARβ axis in Ucp3 gene induction

Tanes I. Lima, Dimitrius Guimaraes, Carlos H. Sponton, Marcio C. Bajgelman, Soledad Palameta, Jessica M. Toscaro, Osvaldo Reis, Leonardo R. Silveira


										

Essential role of the PGC‐1α/PPARβ axis in Ucp3 gene induction

Tanes I. Lima, Dimitrius Guimaraes, Carlos H. Sponton, Marcio C. Bajgelman, Soledad Palameta, Jessica M. Toscaro, Osvaldo Reis, Leonardo R. Silveira

    Fontes

    Journal of physiology

    Vol. 597, no. 16 (Aug., 2019), p. 4277-4291