Neuroprotective effect of tempol (4 hydroxy-tempo) on neuronal death induced by sciatic nerve transection in neonatal rats

Chiarotto, Gabriela Bortolança; Cavarretto, Gabriela; Bombeiro, André Luis; Oliveira, Alexandre Leite Rodrigues de

Neuroprotective effect of tempol (4 hydroxy-tempo) on neuronal death induced by sciatic nerve transection in neonatal rats

Gabriela Bortolanca Chiarotto, Luisa Drummond, Gabriela Cavarretto, André Luis Bombeiro, Alexandre Leite Rodrigues de Oliveira

Material

ARTIGO

Idioma

Inglês

Resumo

Peripheral nerve injury in newborn rats triggers extensive neuronal death within the spinal cord. Because most neurodegeneration is related to oxidative stress and apoptosis, the use of antioxidants may be of therapeutic interest. Tempol is promising beca

Nota de informação sobre financiamento

CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP

Direito de acesso

Fechado

Assuntos

Nervo isquiático

Apoptose

Medula espinhal

Tempol

Neurônios motores

Neuroproteção

Artigo de pesquisa

Autoria

Chiarotto, Gabriela Bortolança, 1989-

Cavarretto, Gabriela

Bombeiro, André Luis

Oliveira, Alexandre Leite Rodrigues de, 1971-

Sites

DOI: https://doi.org/10.1016/j.brainresbull.2014.04.010

Texto completo: https://www.sciencedirect.com/science/article/pii/S0361923014000641

Neuroprotective effect of tempol (4 hydroxy-tempo) on neuronal death induced by sciatic nerve transection in neonatal rats

Gabriela Bortolanca Chiarotto, Luisa Drummond, Gabriela Cavarretto, André Luis Bombeiro, Alexandre Leite Rodrigues de Oliveira

Neuroprotective effect of tempol (4 hydroxy-tempo) on neuronal death induced by sciatic nerve transection in neonatal rats

Gabriela Bortolanca Chiarotto, Luisa Drummond, Gabriela Cavarretto, André Luis Bombeiro, Alexandre Leite Rodrigues de Oliveira

Fontes

Brain research bulletin Vol. 106 (July, 2014), p. 1-8