High Delta Np73/TAp73 ratio is associated with poor prognosis in acute promyelocytic leukemia

High Delta Np73/TAp73 ratio is associated with poor prognosis in acute promyelocytic leukemia

Antonio R. Lucena-Araujo, Haesook T. Kim, Carolina Thome, Rafael H. Jacomo, Raul A. Melo, Rosane Bittencourt, Ricardo Pasquini, Katia Pagnano, Ana Beatriz F. Gloria, Maria de Lourdes Chauffaille, Melina Athayde, Carlos S. Chiattone, Ingrid Mito, Rodrigo Bendlin, Carmino Souza, Cristina Bortolheiro,...

ARTIGO

Inglês

The TP73 gene transcript is alternatively spliced and translated into the transcriptionally active (TAp73) or inactive (Delta Np73) isoforms, with opposite effects on the expression of p53 target genes and on apoptosis induction. The imbalance between Delta Np73 and TAp73 may contribute to...

CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP

Fechado

High Delta Np73/TAp73 ratio is associated with poor prognosis in acute promyelocytic leukemia

Antonio R. Lucena-Araujo, Haesook T. Kim, Carolina Thome, Rafael H. Jacomo, Raul A. Melo, Rosane Bittencourt, Ricardo Pasquini, Katia Pagnano, Ana Beatriz F. Gloria, Maria de Lourdes Chauffaille, Melina Athayde, Carlos S. Chiattone, Ingrid Mito, Rodrigo Bendlin, Carmino Souza, Cristina Bortolheiro,...


										

High Delta Np73/TAp73 ratio is associated with poor prognosis in acute promyelocytic leukemia

Antonio R. Lucena-Araujo, Haesook T. Kim, Carolina Thome, Rafael H. Jacomo, Raul A. Melo, Rosane Bittencourt, Ricardo Pasquini, Katia Pagnano, Ana Beatriz F. Gloria, Maria de Lourdes Chauffaille, Melina Athayde, Carlos S. Chiattone, Ingrid Mito, Rodrigo Bendlin, Carmino Souza, Cristina Bortolheiro,...

    Fontes

    Blood: the journal of hematology

    Vol. 126, no. 20 (Nov., 2015), p. 2302-2306