S100A8 acts as an autocrine priming signal for heme-induced human M phi pro-inflammatory responses in hemolytic inflammation

S100A8 acts as an autocrine priming signal for heme-induced human M phi pro-inflammatory responses in hemolytic inflammation

Angelica A. A. Silveira, Olwyn R. Mahon, Clare C. Cunningham, Emma M. Corr, Rafaela Mendonca, Sara T. O. Saad, Fernando F. Costa, Aisling Dunne, Nicola Conran

ARTIGO

Inglês

Intravascular hemolysis, in addition to reducing red cell counts, incurs extensive vascular inflammation and oxidative stress. One product of hemolysis, heme, is a potent danger associated molecular pattern (DAMP), activating leukocytes and inducing cytokine expression and processing, among other...

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP

fechado

S100A8 acts as an autocrine priming signal for heme-induced human M phi pro-inflammatory responses in hemolytic inflammation

Angelica A. A. Silveira, Olwyn R. Mahon, Clare C. Cunningham, Emma M. Corr, Rafaela Mendonca, Sara T. O. Saad, Fernando F. Costa, Aisling Dunne, Nicola Conran


										

S100A8 acts as an autocrine priming signal for heme-induced human M phi pro-inflammatory responses in hemolytic inflammation

Angelica A. A. Silveira, Olwyn R. Mahon, Clare C. Cunningham, Emma M. Corr, Rafaela Mendonca, Sara T. O. Saad, Fernando F. Costa, Aisling Dunne, Nicola Conran

    Fontes

    Journal of leukocyte biology

    Vol. 106, no. 1, nespTargeted Science (July, 2019), p. 35-43