To evaluate root dentine demineralisation, biomass and loosely bound fluoride (CaF2) concentration according to different frequencies of sucrose exposure using a high-fluoride dentifrice. Although high-fluoride dentifrice has been recommended to arrest root dentine lesions, it is not clear whether...

To evaluate root dentine demineralisation, biomass and loosely bound fluoride (CaF2) concentration according to different frequencies of sucrose exposure using a high-fluoride dentifrice. Although high-fluoride dentifrice has been recommended to arrest root dentine lesions, it is not clear whether it can protect dentine from increased frequencies of sucrose exposure. An in situ, crossover, split-mouth study was conducted in 3 phases with 7 days each, in which 10 volunteers used a palatal device containing 4 bovine root dentine slabs (2 on each side) with predetermined initial hardness. Cariogenic challenge consisted in dripping a 20% sucrose solution 0 (control), 2, 4, 6, 8 or 10 times/d in each block. Volunteers used high-fluoride dentifrice (NaF, 5000 mu g F/g) 3 times/d. After each phase, final hardness was measured and the percentage of surface hardness loss (%SHL) calculated. Also, biomass and CaF2 concentration on dentine were determined. The data were processed and analysed by ANOVA and Tukey test with significance level set at 5%. The relationship between the variables was analysed by linear regression and Pearson correlation (r). Results %SHL and biomass were significantly greater than control for sucrose frequencies higher than 6 times/d (P < 0.001), while CaF2 concentration decreased from sucrose frequency higher than 2 times/d (P < 0.001). Regression analysis data showed a significant linear fit between sucrose exposure frequency and the studied variables with a strong correlation (r) for %SHL and CaF2 and moderate for biomass (P < 0.05). High-fluoride dentifrice is able to reduce root dentine demineralisation if sucrose consumption is not higher than 6 times/d

CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ

474318/2013-3

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