Hypoxic niches are endowed with a protumorigenic mechanism that supersedes the protective function of PTEN

Hypoxic niches are endowed with a protumorigenic mechanism that supersedes the protective function of PTEN

Carlos H. V. Nascimento-Filho, Liana P. Webber, Gabriell B. Borgato, Eny M. Goloni-Bertollo, Cristiane H. Squarize, Rogerio M. Castilho

ARTIGO

Inglês

Agradecimentos: This work was conducted during a visiting scholar period at the University of Michigan, sponsored by the Capes Foundation within the Brazilian Ministry of Education (Grant BEX/88881.135014/2016-01 PDSE). This work was partially supported by University of Michigan Cancer Center...

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide and is characterized by a fast-paced growth. Like other solid tumors, the HNSCC growth rate results in the development of hypoxic regions identified by the expression of hypoxia-inducible factor 1 alpha...

COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPES

Fechado

Hypoxic niches are endowed with a protumorigenic mechanism that supersedes the protective function of PTEN

Carlos H. V. Nascimento-Filho, Liana P. Webber, Gabriell B. Borgato, Eny M. Goloni-Bertollo, Cristiane H. Squarize, Rogerio M. Castilho


										

Hypoxic niches are endowed with a protumorigenic mechanism that supersedes the protective function of PTEN

Carlos H. V. Nascimento-Filho, Liana P. Webber, Gabriell B. Borgato, Eny M. Goloni-Bertollo, Cristiane H. Squarize, Rogerio M. Castilho

    Fontes

    The FASEB journal

    Vol. 33, no. 12 (Dec., 2019), p. 13435-13449