Leiomyomatous hamartomas of the oral cavity : clinicopathological and immunohistochemical features of 4 cases and literature review
Celeste Sanchez-Romero, Paulo Rogerio Ferreti Bonan, Fabio Ramoa Pires, Geraldo Oliveira Silva-Junior, Wilson Delgado Azanero, Oslei Paes de Almeida, Danyel Elias da Cruz Perez
ARTIGO
Inglês
To present 4 new cases of oral leiomyomatous hamartomas (OLH), describing its clinical, microscopical, and immunohistochemical features, and a literature review. Methods. The OLH cases were retrieved from the files of 2 Brazilian and 1 Peruvian oral pathology services. Clinical data were obtained...
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To present 4 new cases of oral leiomyomatous hamartomas (OLH), describing its clinical, microscopical, and immunohistochemical features, and a literature review. Methods. The OLH cases were retrieved from the files of 2 Brazilian and 1 Peruvian oral pathology services. Clinical data were obtained from the pathology reports. Microscopical features were reviewed, and immunohistochemical reactions were performed. A review of the English-language literature about OLH was done. Results. The sample was composed of 3 females (4-, 10-, and 15-year-old) and 1 male (3-year-old). Three cases affected the dorsum of the tongue and one the incisive papilla, and all presented sessile or pedunculated smooth nodules. Microscopically, the lesions were composed of varying-size fascicles of smooth muscle fibers in a fibrous connective tissue background. Immunohistochemistry revealed positivity of the smooth muscle bundles for myogenic markers. The English-language literature review revealed 38 OLH cases reported, most were congenital or diagnosed up to 5 years old. The main locations were tongue and anterior maxilla. Conclusions. Although OLH is a rare lesion, it must be considered in the differential diagnosis of midline tongue or maxillary masses in newborns, infants, and youngsters
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COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPES
Fechado
Leiomyomatous hamartomas of the oral cavity : clinicopathological and immunohistochemical features of 4 cases and literature review
Celeste Sanchez-Romero, Paulo Rogerio Ferreti Bonan, Fabio Ramoa Pires, Geraldo Oliveira Silva-Junior, Wilson Delgado Azanero, Oslei Paes de Almeida, Danyel Elias da Cruz Perez
Leiomyomatous hamartomas of the oral cavity : clinicopathological and immunohistochemical features of 4 cases and literature review
Celeste Sanchez-Romero, Paulo Rogerio Ferreti Bonan, Fabio Ramoa Pires, Geraldo Oliveira Silva-Junior, Wilson Delgado Azanero, Oslei Paes de Almeida, Danyel Elias da Cruz Perez
Fontes
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International journal of surgical pathology Vol. 27, no. 6 (Sep., 2019), p. 624-630 |