DMH-CBD, a cannabidiol analog with reduced cytotoxicity, inhibits TNF production by targeting NF-kB activity dependent on A(2A) receptor

DMH-CBD, a cannabidiol analog with reduced cytotoxicity, inhibits TNF production by targeting NF-kB activity dependent on A(2A) receptor

Rangel L. Silva, Gabriela T. Silveira, Carlos W. Wanderlei, Nerry T. Cecilio, Alexandre G. M. Maganin, Marcelo Franchin, Lucas M. M. Marques, Norberto P. Lopes, Jose A. Crippa, Francisco S. Guimaraes, Jose C. F. Alves, Fernando Q. Cunha, Thiago M. Cunha

ARTIGO

Inglês

Cannabidiol (CBD) is a natural compound with psychoactive therapeutic properties well described. Conversely, the immunological effects of CBD are still poorly explored. In this study, the potential anti-inflammatory effects and underlying mechanisms of CBD and its analog Dimethyl-Heptyl-Cannabidiol...

CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP

Fechado

DMH-CBD, a cannabidiol analog with reduced cytotoxicity, inhibits TNF production by targeting NF-kB activity dependent on A(2A) receptor

Rangel L. Silva, Gabriela T. Silveira, Carlos W. Wanderlei, Nerry T. Cecilio, Alexandre G. M. Maganin, Marcelo Franchin, Lucas M. M. Marques, Norberto P. Lopes, Jose A. Crippa, Francisco S. Guimaraes, Jose C. F. Alves, Fernando Q. Cunha, Thiago M. Cunha


										

DMH-CBD, a cannabidiol analog with reduced cytotoxicity, inhibits TNF production by targeting NF-kB activity dependent on A(2A) receptor

Rangel L. Silva, Gabriela T. Silveira, Carlos W. Wanderlei, Nerry T. Cecilio, Alexandre G. M. Maganin, Marcelo Franchin, Lucas M. M. Marques, Norberto P. Lopes, Jose A. Crippa, Francisco S. Guimaraes, Jose C. F. Alves, Fernando Q. Cunha, Thiago M. Cunha

    Fontes

    Toxicology and applied pharmacology

    Vol. 368 (Apr., 2019), p. 63-71