The fatty acid synthase inhibitor orlistat reduces the growth and metastasis of orthotopic tongue oral squamous cell carcinomas

The fatty acid synthase inhibitor orlistat reduces the growth and metastasis of orthotopic tongue oral squamous cell carcinomas

M. Agostini, L.Y. Almeida, D.C. Bastos, R.M. Ortega, F.S. Moreira, F. Seguin, K.G. Zecchin, H.F. Raposo, H.C.F. Oliveira, N.D. Amoedo, T. Salo, R.D. Coletta, E. Graner

ARTIGO

Inglês

Fatty acid synthase (FASN) is the biosynthetic enzyme responsible for the endogenous synthesis of fatty acids. It is downregulated in most normal cells, except in lipogenic tissues such as liver, lactating breast, fetal lung, and adipose tissue. Conversel

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP

Fechado

The fatty acid synthase inhibitor orlistat reduces the growth and metastasis of orthotopic tongue oral squamous cell carcinomas

M. Agostini, L.Y. Almeida, D.C. Bastos, R.M. Ortega, F.S. Moreira, F. Seguin, K.G. Zecchin, H.F. Raposo, H.C.F. Oliveira, N.D. Amoedo, T. Salo, R.D. Coletta, E. Graner


										

The fatty acid synthase inhibitor orlistat reduces the growth and metastasis of orthotopic tongue oral squamous cell carcinomas

M. Agostini, L.Y. Almeida, D.C. Bastos, R.M. Ortega, F.S. Moreira, F. Seguin, K.G. Zecchin, H.F. Raposo, H.C.F. Oliveira, N.D. Amoedo, T. Salo, R.D. Coletta, E. Graner

    Fontes

    Molecular cancer therapeutics

    Vol. 13, no. 3 (2014), p. 585-595