The fatty acid synthase inhibitor orlistat reduces the growth and metastasis of orthotopic tongue oral squamous cell carcinomas
M. Agostini, L.Y. Almeida, D.C. Bastos, R.M. Ortega, F.S. Moreira, F. Seguin, K.G. Zecchin, H.F. Raposo, H.C.F. Oliveira, N.D. Amoedo, T. Salo, R.D. Coletta, E. Graner
ARTIGO
Inglês
Fatty acid synthase (FASN) is the biosynthetic enzyme responsible for the endogenous synthesis of fatty acids. It is downregulated in most normal cells, except in lipogenic tissues such as liver, lactating breast, fetal lung, and adipose tissue. Conversel
FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP
2008/57471-7; 2008/55548-2; 2012/25160-8; 2010/51090-1; 2010/52635-1; 2010/50946-0
Fechado
The fatty acid synthase inhibitor orlistat reduces the growth and metastasis of orthotopic tongue oral squamous cell carcinomas
M. Agostini, L.Y. Almeida, D.C. Bastos, R.M. Ortega, F.S. Moreira, F. Seguin, K.G. Zecchin, H.F. Raposo, H.C.F. Oliveira, N.D. Amoedo, T. Salo, R.D. Coletta, E. Graner
The fatty acid synthase inhibitor orlistat reduces the growth and metastasis of orthotopic tongue oral squamous cell carcinomas
M. Agostini, L.Y. Almeida, D.C. Bastos, R.M. Ortega, F.S. Moreira, F. Seguin, K.G. Zecchin, H.F. Raposo, H.C.F. Oliveira, N.D. Amoedo, T. Salo, R.D. Coletta, E. Graner
Fontes
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Molecular cancer therapeutics Vol. 13, no. 3 (2014), p. 585-595 |