Fluoride release from Caf2 and enamel demineralization
L.M.A. Tenuta, R.V. Cerezetti, A.A. Del Bel Cury, C.P.M. Tabchoury, J.A. Cury
ARTIGO
Inglês
The anticaries effect of professional fluoride (F) application has been attributed to calcium-fluoride-like deposits (CaF2) formed on enamel, but this has not been clearly demonstrated. We hypothesized that CaF2 formed on plaque-free enamel by F application would reduce enamel demineralization due...
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The anticaries effect of professional fluoride (F) application has been attributed to calcium-fluoride-like deposits (CaF2) formed on enamel, but this has not been clearly demonstrated. We hypothesized that CaF2 formed on plaque-free enamel by F application would reduce enamel demineralization due to the increase of F availability in fluid of subsequently formed plaque. We created distinct levels of CaF2 on enamel to evaluate a dose-response effect. Enamel blocks were mounted in contact with a S. mutans test plaque and used in situ by 10 volunteers. F released to the fluid phase of this substrate (“plaque fluid”) was measured before a cariogenic challenge. “Plaque fluid” F concentration was highly correlated to the enamel CaF2 concentration (r = 0.96, p < 0.001) and to consequent enamel demineralization (r = −0.75, p < 0.001). The results suggest that F released to plaque fluid from CaF2 formed on enamel may play a significant role in the anticaries effect of professionally applied F agents
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FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP
2005/04703-0
CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ
fechado
Fluoride release from Caf2 and enamel demineralization
L.M.A. Tenuta, R.V. Cerezetti, A.A. Del Bel Cury, C.P.M. Tabchoury, J.A. Cury
Fluoride release from Caf2 and enamel demineralization
L.M.A. Tenuta, R.V. Cerezetti, A.A. Del Bel Cury, C.P.M. Tabchoury, J.A. Cury
Fontes
Journal of dental research (Fonte avulsa) |