Gonadal hormones decrease temporomandibular joint kappa-mediated antinociception through a down-regulation in the expression of kappa opioid receptors in the trigeminal ganglia

Gonadal hormones decrease temporomandibular joint kappa-mediated antinociception through a down-regulation in the expression of kappa opioid receptors in the trigeminal ganglia

J. T. Clemente-Napimoga, A. Pellegrini-da-Silva, V. H. A. Ferreira, M. H. Napimoga, C. A. Parada, C. H. Tambeli

ARTIGO

Inglês

We have previously demonstrated that activation of kappa-opioid receptor located in the temporomandibular joint (TMJ) of rats induces a significantly greater TMJ antinociception in diestrus females than in proestrus females (higher estradiol serum levels than diestrus) and males. These findings...

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Gonadal hormones decrease temporomandibular joint kappa-mediated antinociception through a down-regulation in the expression of kappa opioid receptors in the trigeminal ganglia

J. T. Clemente-Napimoga, A. Pellegrini-da-Silva, V. H. A. Ferreira, M. H. Napimoga, C. A. Parada, C. H. Tambeli


										

Gonadal hormones decrease temporomandibular joint kappa-mediated antinociception through a down-regulation in the expression of kappa opioid receptors in the trigeminal ganglia

J. T. Clemente-Napimoga, A. Pellegrini-da-Silva, V. H. A. Ferreira, M. H. Napimoga, C. A. Parada, C. H. Tambeli

    Fontes

    European journal of pharmacology

    Vol. 617, no. 1-3 (Sept., 2009), p. 41-47