BackgroundPrevious studies have shown during the orthodontic treatment, the prevalence of active caries lesions (ACL) in 30 to 70% of patients.
AimTo evaluate the effect of orthodontic treatment on salivary properties considering caries development.
DesignTwenty two individuals (11-22 years) were...

BackgroundPrevious studies have shown during the orthodontic treatment, the prevalence of active caries lesions (ACL) in 30 to 70% of patients.
AimTo evaluate the effect of orthodontic treatment on salivary properties considering caries development.
DesignTwenty two individuals (11-22 years) were assessed regarding caries, oral hygiene, sugar exposure, salivary flow rate (SFR), buffering capacity, pH, carbonic anhydrase VI (CA VI) and amylase activity, at baseline, 1, 3 and 6 months after the orthodontic appliances placement. Caries index was determined by Nyvad criteria. CA VI and amylase activities were performed by zymography and ELISA, respectively.
ResultsBuffering capacity decreased after 3 months (P < 0.0001) and showed positive correlation with pH at baseline and after 1 month in individuals who did not develop active caries lesions. Amylase activity decreased after 1 and 6 months (P = 0.0003) and presented positive correlation with CA VI in patients who developed ACL. SFR increased after 1 month (P = 0.0283) and showed positive correlation with CA VI activity after 3 months in individuals who did not develop ACL. Salivary pH showed negative correlation with CA VI after 1 month in patients who did not develop ACL. ACL were firstly diagnosed after 3 months.
ConclusionsThe present study demonstrated that saliva of individuals under orthodontic treatment is subjected to changes in properties that have implications on the onset of ACL

COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPES

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