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Lonchocarpus sericeus lectin decreases leukocyte migration and mechanical hypernociception by inhibiting cytokine and chemokines production

Lonchocarpus sericeus lectin decreases leukocyte migration and mechanical hypernociception by inhibiting cytokine and chemokines production

M. H. Napimoga, B. S. Cavada, N. M. N. Alencar, M. L. Mota, F. S. Bittencourt, J. C. Alves, R. Grespan, R. B. Goncalves, J. T. Clemente-Napimoga, A. de Freitas, C. A. Parada, S. H. Ferreira, F. Q. Cunha

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Agradecimentos: The authors would like to thank Mrs. Ieda R. Schivo and Giuliana Bertozi for their technical assistance.

Abstract: In this study, we tested the potential use of a lectin from Lonchocarpus sericeus seeds (LSL), to control neutrophil migration and inflammatory hypernociception (decrease of nociceptive threshold). Pretreatment of the animals intravenously (15 min before) with LSL inhibited neutrophil... Ver mais

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Lonchocarpus sericeus lectin decreases leukocyte migration and mechanical hypernociception by inhibiting cytokine and chemokines production

M. H. Napimoga, B. S. Cavada, N. M. N. Alencar, M. L. Mota, F. S. Bittencourt, J. C. Alves, R. Grespan, R. B. Goncalves, J. T. Clemente-Napimoga, A. de Freitas, C. A. Parada, S. H. Ferreira, F. Q. Cunha

										

Lonchocarpus sericeus lectin decreases leukocyte migration and mechanical hypernociception by inhibiting cytokine and chemokines production

M. H. Napimoga, B. S. Cavada, N. M. N. Alencar, M. L. Mota, F. S. Bittencourt, J. C. Alves, R. Grespan, R. B. Goncalves, J. T. Clemente-Napimoga, A. de Freitas, C. A. Parada, S. H. Ferreira, F. Q. Cunha

    Fontes

    International immunopharmacology (Fonte avulsa)