Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis, cisplatin sensitivity and lymph node metastasis in xenograft tumor models

Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis, cisplatin sensitivity and lymph node metastasis in xenograft tumor models

L. O. Sousa, H. Cabral, L. M. Sobral, J. S. Gutkind, L. J. Greene, R. D. Coletta, E. H. Tajara, C. Curti, A. M. Leopoldino

ARTIGO

Inglês

SET/I2PP2A is a multifunctional protein that is up-regulated in head and neck squamous cell carcinoma (HNSCC). The action of SET in HNSCC tumorigenicity is unknown. Stable SET knockdown by shRNA (shSET) was established in three HNSCC cell lines: HN12, HN13, and Cal27. Protein expression and...

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP

CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ

Fechado

Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis, cisplatin sensitivity and lymph node metastasis in xenograft tumor models

L. O. Sousa, H. Cabral, L. M. Sobral, J. S. Gutkind, L. J. Greene, R. D. Coletta, E. H. Tajara, C. Curti, A. M. Leopoldino


										

Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis, cisplatin sensitivity and lymph node metastasis in xenograft tumor models

L. O. Sousa, H. Cabral, L. M. Sobral, J. S. Gutkind, L. J. Greene, R. D. Coletta, E. H. Tajara, C. Curti, A. M. Leopoldino

    Fontes

    Molecular Cancer

    Vol. 13 (Feb., 2014), n. art. 32