Biocompatibility evaluation of Epiphany/Resilon root canal filling system in subcutaneous tissue of rats
Lucas da Fonseca Roberti Garcia, André Augusto Franco Marques, Lourenço de Moraes Rego Roselino, Fernanda de Carvalho Panzeri Pires-de-Souza, Simonides Consani
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The purpose of this study was to evaluate the biocompatibility of the root canal filling system Epiphany/Resilon in connective tissue of rats. Methods: Fifteen rats were used, separated into 3 groups in accordance with its period of death (7, 21, 42 days). Four filled dentin tubes were implanted...
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The purpose of this study was to evaluate the biocompatibility of the root canal filling system Epiphany/Resilon in connective tissue of rats. Methods: Fifteen rats were used, separated into 3 groups in accordance with its period of death (7, 21, 42 days). Four filled dentin tubes were implanted with the tested materials as follows: ERSP group, Epiphany/Resilon with Self-etch Primer; ER group, Epiphany/Resilon without primer; EG group, Endofill/gutta-percha points; and ET group, empty tube. After 7, 21, and 42 days, animals were killed, obtaining 5 samples per group. A grade from I–IV was used to graduate the inflammatory reaction. Results: Results showed that Epiphany/Resilon (ERSP and ER groups) induced a slight (II) inflammatory reaction after 42 days. However, in ER group, in which the self-etch primer was not applied, severe (IV) to moderate (III) inflammatory reactions were observed between 7 and 21 days. When compared with the EG and ET groups, it was observed that these groups presented tissue reaction ranging from slight (II, 7 and 21 days) to no inflammation (I, 42 days). Conclusions: Epiphany/Resilon root canal filling system presented satisfactory tissue reaction. It was biocompatible when tested in connective tissue of rats.
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Biocompatibility evaluation of Epiphany/Resilon root canal filling system in subcutaneous tissue of rats
Lucas da Fonseca Roberti Garcia, André Augusto Franco Marques, Lourenço de Moraes Rego Roselino, Fernanda de Carvalho Panzeri Pires-de-Souza, Simonides Consani
Biocompatibility evaluation of Epiphany/Resilon root canal filling system in subcutaneous tissue of rats
Lucas da Fonseca Roberti Garcia, André Augusto Franco Marques, Lourenço de Moraes Rego Roselino, Fernanda de Carvalho Panzeri Pires-de-Souza, Simonides Consani
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Journal of endodontics Vol. 36, no. 1 (Jan., 2010), p. 110-114 |