Biocompatibility evaluation of Epiphany/Resilon root canal filling system in subcutaneous tissue of rats
Lucas da Fonseca Roberti Garcia, André Augusto Franco Marques, Lourenço de Moraes Rego Roselino, Fernanda de Carvalho Panzeri Pires-de-Souza, Simonides Consani
ARTIGO
Inglês
The purpose of this study was to evaluate the biocompatibility of the root canal filling system Epiphany/Resilon in connective tissue of rats. Methods: Fifteen rats were used, separated into 3 groups in accordance with its period of death (7, 21, 42 days). Four filled dentin tubes were implanted...
The purpose of this study was to evaluate the biocompatibility of the root canal filling system Epiphany/Resilon in connective tissue of rats. Methods: Fifteen rats were used, separated into 3 groups in accordance with its period of death (7, 21, 42 days). Four filled dentin tubes were implanted with the tested materials as follows: ERSP group, Epiphany/Resilon with Self-etch Primer; ER group, Epiphany/Resilon without primer; EG group, Endofill/gutta-percha points; and ET group, empty tube. After 7, 21, and 42 days, animals were killed, obtaining 5 samples per group. A grade from I–IV was used to graduate the inflammatory reaction. Results: Results showed that Epiphany/Resilon (ERSP and ER groups) induced a slight (II) inflammatory reaction after 42 days. However, in ER group, in which the self-etch primer was not applied, severe (IV) to moderate (III) inflammatory reactions were observed between 7 and 21 days. When compared with the EG and ET groups, it was observed that these groups presented tissue reaction ranging from slight (II, 7 and 21 days) to no inflammation (I, 42 days). Conclusions: Epiphany/Resilon root canal filling system presented satisfactory tissue reaction. It was biocompatible when tested in connective tissue of rats.
Fechado
Biocompatibility evaluation of Epiphany/Resilon root canal filling system in subcutaneous tissue of rats
Lucas da Fonseca Roberti Garcia, André Augusto Franco Marques, Lourenço de Moraes Rego Roselino, Fernanda de Carvalho Panzeri Pires-de-Souza, Simonides Consani
Biocompatibility evaluation of Epiphany/Resilon root canal filling system in subcutaneous tissue of rats
Lucas da Fonseca Roberti Garcia, André Augusto Franco Marques, Lourenço de Moraes Rego Roselino, Fernanda de Carvalho Panzeri Pires-de-Souza, Simonides Consani
Fontes
Journal of endodontics Vol. 36, no. 1 (Jan., 2010), p. 110-114 |