Silk fibroin and sodium alginate blend : Miscibility and physical characteristics
Mariana Agostini de Moraes, Mariana Ferreira Silva, Raquel Farias Weska, Marisa Masumi Beppu
ARTIGO
Inglês
Films of silk fibroin (SF) and sodium alginate (SA) blends were prepared by solution casting technique. The miscibility of SF and SA in those blends was evaluated and scanning electron microscopy (SEM) revealed that SF/SA 25/75 wt.% blends underwent microscopic phase separation, resulting in...
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Films of silk fibroin (SF) and sodium alginate (SA) blends were prepared by solution casting technique. The miscibility of SF and SA in those blends was evaluated and scanning electron microscopy (SEM) revealed that SF/SA 25/75 wt.% blends underwent microscopic phase separation, resulting in globular structures composed mainly of SF. X-ray diffraction indicated the amorphous nature of these blends, even after a treatment with ethanol that turned them insoluble in water. Thermal analyses of blends showed the peaks of degradation of pristine SF and SA shifted to intermediate temperatures. Water vapor permeability, swelling capacity and tensile strength of SF films could be enhanced by blending with SA. Cell viability remained between 90 and 100%, as indicated by in vitro cytotoxicity test. The SF/SA blend with self-assembled SF globules can be used to modulate structural and mechanical properties of the final material and may be used in designing high performance wound dressing
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FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP
CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ
Fechado
Silk fibroin and sodium alginate blend : Miscibility and physical characteristics
Mariana Agostini de Moraes, Mariana Ferreira Silva, Raquel Farias Weska, Marisa Masumi Beppu
Silk fibroin and sodium alginate blend : Miscibility and physical characteristics
Mariana Agostini de Moraes, Mariana Ferreira Silva, Raquel Farias Weska, Marisa Masumi Beppu
Fontes
Materials science and engineering C: materials for biological applications (Fonte avulsa) |