Analysis of phase transition and dehydration processes of nevirapine
George G. G. de Oliveira, Humberto G. Ferraz, Patricia Severino, Eliana B. Souto
ARTIGO
Inglês
Solid-state characterization of crystalline drugs is an important pre-formulation step for the development and design of solid dosage forms, such as pellets and tablets. In this study, phase transition and dehydration processes of nevirapine have been studied by differential scanning calorimetry and...
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Solid-state characterization of crystalline drugs is an important pre-formulation step for the development and design of solid dosage forms, such as pellets and tablets. In this study, phase transition and dehydration processes of nevirapine have been studied by differential scanning calorimetry and thermogravimetry differential thermal analysis to overcome the problems of drug formulation, namely poor solubility and poor content uniformity. Phase solubility studies elucidated the mechanism of enhanced nevirapine solubility.
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COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPES
FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP
Fechado
Analysis of phase transition and dehydration processes of nevirapine
George G. G. de Oliveira, Humberto G. Ferraz, Patricia Severino, Eliana B. Souto
Analysis of phase transition and dehydration processes of nevirapine
George G. G. de Oliveira, Humberto G. Ferraz, Patricia Severino, Eliana B. Souto
Fontes
Journal of thermal analysis and calorimetry (Fonte avulsa) |