1,2,3-Triazole tethered 2-mercaptobenzimidazole derivatives : design, synthesis and molecular assessment toward C6 glioma cell line

1,2,3-Triazole tethered 2-mercaptobenzimidazole derivatives : design, synthesis and molecular assessment toward C6 glioma cell line

Peterson de Andrade, Amanda de Fraga Dias, Fabrício Figueiró, Fernando Cidade Torres, Daniel Fábio Kawano, Ana Maria Oliveira Battastini, Ivone Carvalho, Carlos Henrique Tomich de Paula da Silva, Joaquín Maria Campos

ARTIGO

Inglês

Glioblastoma multiforme (GBM) is an aggressive cancer with very limited clinical therapies. Herein, we have designed novel mercaptobenzimidazole derivatives (1–7) as multitarget antineoplastic drugs and assessed their antiproliferative profiles on an experimental model for GBM, the C6 glioma line....

Fechado

1,2,3-Triazole tethered 2-mercaptobenzimidazole derivatives : design, synthesis and molecular assessment toward C6 glioma cell line

Peterson de Andrade, Amanda de Fraga Dias, Fabrício Figueiró, Fernando Cidade Torres, Daniel Fábio Kawano, Ana Maria Oliveira Battastini, Ivone Carvalho, Carlos Henrique Tomich de Paula da Silva, Joaquín Maria Campos


										

1,2,3-Triazole tethered 2-mercaptobenzimidazole derivatives : design, synthesis and molecular assessment toward C6 glioma cell line

Peterson de Andrade, Amanda de Fraga Dias, Fabrício Figueiró, Fernando Cidade Torres, Daniel Fábio Kawano, Ana Maria Oliveira Battastini, Ivone Carvalho, Carlos Henrique Tomich de Paula da Silva, Joaquín Maria Campos

    Fontes

    Future medicinal chemistry

    Vol. 12, no. 8 (Mar., 2020)