Fibrous PCL/PLLA scaffolds obtained by rotary spinning and electrospinning
Talita Almeida Vida, Adriana Cristina Motta, Arnaldo Rodrigues Santos Jr., Guinea Brasil Camargo Cardoso, Crystopher Cardoso de Brito, Cecília Amélia de Carvalho Zavaglia
ARTIGO
Inglês
Agradecimentos: The authors gratefully acknowledge financial support provided by CAPES, FAPESP (grant 2013/19372-0), Biofabris-INCT and Biomaterials Laboratory PUC/SP Sorocaba
Rotary jet spinning (RJS) and electrospinning are techniques to obtain fibrous scaffolds. RJS is a simple method, which fabricates three-dimensional fibers by exploiting a high-speed rotating nozzle, creating a polymer jet which stretches until solidification, and does not require high voltage. In...
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Rotary jet spinning (RJS) and electrospinning are techniques to obtain fibrous scaffolds. RJS is a simple method, which fabricates three-dimensional fibers by exploiting a high-speed rotating nozzle, creating a polymer jet which stretches until solidification, and does not require high voltage. In opposite, electrospinning technique needs the presence of an external electric field to create fiber from the polymeric jet solution. This article investigates both processes using two different biocompatible polymers: Poly(L-lactic acid) (PLLA) and Poly(ε-caprolactone) (PCL). Samples were characterized by scanning electron microscopy, thermogravimetric analysis, differential scanning calorimeter, and Fourier-transform infrared spectroscopy. Morphological observations showed the efficiency of both techniques in obtaining nanofibers. Thermal analyses of data indicate immiscible property of different blends and the total solvent evaporation. In vitro cytocompatibility test showed that RJS and electrospinning samples exhibited good cytocompatibility. Based on these results, it may be concluded that the fibers obtained with both technologies are non-cytotoxicity and with good biocompatibility, and might be suitable for applications as scaffold for cell growth
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COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPES
FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP
2013/19372-0
Fechado
Fibrous PCL/PLLA scaffolds obtained by rotary spinning and electrospinning
Talita Almeida Vida, Adriana Cristina Motta, Arnaldo Rodrigues Santos Jr., Guinea Brasil Camargo Cardoso, Crystopher Cardoso de Brito, Cecília Amélia de Carvalho Zavaglia
Fibrous PCL/PLLA scaffolds obtained by rotary spinning and electrospinning
Talita Almeida Vida, Adriana Cristina Motta, Arnaldo Rodrigues Santos Jr., Guinea Brasil Camargo Cardoso, Crystopher Cardoso de Brito, Cecília Amélia de Carvalho Zavaglia
Fontes
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Materials research Vol. 20, no. 2 (Mar., 2018), p. 910-916 |