RFID (Radio Frequency Identification) systems are meant to increase accuracy and velocity in objects identification, supporting Industry 4.0. However, there are challenges that need to be faced. This paper aims to identify and analyse the main difficulties regarding RFID systems implementation. We combined both systematic literature review and survey methods with ninety RFID experts. Data was analysed through Exploratory Factor Analysis. Empirical evidences have led to three main factors explaining most of the variance: operational difficulties, planning difficulties and employee difficulties. This corroborates the literature with recent data sets and provides quantitative analysis for prioritisation during RFID implementation. Professionals can use these research results as a guide to RFID systems implementation to create preventive actions during implementation initiatives. In the context of the Internet of Things and Fourth Industrial Revolution, RFID is considered an emerging topic nowadays, but no similar studies exist in the scientific literature Ver menos