PLLA synthesis and nanofibers production : viability by human mesenchymal stem cell from adipose tissue
ARTIGO
Inglês
Agradecimentos: The authors wish to acknowledge the financial support provided by the Scientific Research Foundation for the State of São Paulo (FAPESP Process 2008/57860-3) and National Council for Scientific and Technological Development (CNPq Process 573661/2008-1)
The absorbable polyacid is one of the most used and studied materials in tissue engineering. This work synthesized a poly (L-lactic acid) (PLLA) through ring-opening polymerization and produced with it nanofibers by the electrospinning process. The PLLA was analyzed by FTIR and its cytotoxicity was...
The absorbable polyacid is one of the most used and studied materials in tissue engineering. This work synthesized a poly (L-lactic acid) (PLLA) through ring-opening polymerization and produced with it nanofibers by the electrospinning process. The PLLA was analyzed by FTIR and its cytotoxicity was evaluated by the MTT assay and Live/Dead (R) (Molecular Probes). The tests were performed in contact with human mesenchymal cells at varying times. The high rates of viability and proliferation of cells in contact with the PLLA shown by MTT and Live/Dead (R) tests demonstrate that this PLLA is a biocompatible material. There was also the successful production of electrospinning nanofibers, which can be converted for specific biomedical applications in the future
Fechado
PLLA synthesis and nanofibers production : viability by human mesenchymal stem cell from adipose tissue
PLLA synthesis and nanofibers production : viability by human mesenchymal stem cell from adipose tissue
Fontes
Procedia CIRP Vol. 49 (2016), p. 213-221 |