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229 registros encontrados - unidade Centro de Biologia Molecular e Engenharia Genética

3D cell-SELEX : development of RNA aptamers as molecular probes for PC-3 tumor cell line
1.

3D cell-SELEX : development of RNA aptamers as molecular probes for PC-3 tumor cell line

ARTIGO - Inglês

Assunto: Neoplasias da próstata

Human prostate cancer (PCa) is a highly heterogeneous and multifactorial disease. Current clinical biomarkers are not sufficiently accurate, thus... Ver mais

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Abnormal expression of inflammatory genes in placentas of women with sickle cell anemia and sickle Hemoglobin C disease
3.

Abnormal expression of inflammatory genes in placentas of women with sickle cell anemia and sickle Hemoglobin C disease

ARTIGO - Inglês

Assunto: Placenta

Sickle cell disease (SCD) is a complex disease that is characterized by the polymerization of deoxyhemoglobin S, altered red blood cell membrane... Ver mais

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A de novo mutation in CYP21A2 gene in a case of in vitro fertilization
5.

A de novo mutation in CYP21A2 gene in a case of in vitro fertilization

ARTIGO - Inglês

Assunto: Proteína CYP21A2 humana

Abstract: Congenital adrenal hyperplasia, one of the most frequent autosome recessive disorders, is caused by defects in steroidogenic enzymes... Ver mais

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Advances in genomic characterization of urochloa humidicola : exploring polyploid inheritance and apomixis
6.

Advances in genomic characterization of urochloa humidicola : exploring polyploid inheritance and apomixis

ARTIGO - Inglês

Assunto: Urochloa humidicola

Abstract: We present the highest-density genetic map for the hexaploid Urochloa humidicola. SNP markers expose genetic organization, reproduction, and... Ver mais

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Advances in genomic characterization of Urochloa humidicola : exploring polyploid inheritance and apomixis
7.

Advances in genomic characterization of Urochloa humidicola : exploring polyploid inheritance and apomixis

PRE-PRINT - Inglês

Assunto: Urochloa humidicola

Abstract: Tropical forage grasses are an important food source for animal feeding, with Urochloa humidicola, also known as Koronivia grass, being one... Ver mais

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A joint learning approach for genomic prediction in polyploid grasses
8.

A joint learning approach for genomic prediction in polyploid grasses

ARTIGO - Inglês

Assunto: Artigo original

Abstract: Poaceae, among the most abundant plant families, includes many economically important polyploid species, such as forage grasses and... Ver mais

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A mixed model QTL analysis for sugarcane multiple-harvest-location trial data
9.

A mixed model QTL analysis for sugarcane multiple-harvest-location trial data

ARTIGO - Inglês

Assunto: Cana-de-açúcar

Sugarcane-breeding programs take at least 12 years to develop new commercial cultivars. Molecular markers offer a possibility to study the genetic... Ver mais

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Analysis of CFB (R32Q - rs641153) and CFH (rs1410996) variants as risk factors for age-related macular degeneration in a brazilian population
10.

Analysis of CFB (R32Q - rs641153) and CFH (rs1410996) variants as risk factors for age-related macular degeneration in a brazilian population

ARTIGO - Inglês

Assunto: Fatores de risco

Age-related macular degeneration (AMD) is a progressive, mutifactorial condition that affects the central retina, and represents an important cause of... Ver mais

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Analysis of mitochondrial alterations in Brazilian patients with sensorineural hearing loss using MALDI-TOF mass spectrometry
11.

Analysis of mitochondrial alterations in Brazilian patients with sensorineural hearing loss using MALDI-TOF mass spectrometry

ARTIGO - Inglês

Assunto: Espectrometria de massa

Mutations in the mitochondrial DNA (mtDNA) have been associated with aminoglycoside-induced and nonsyndromic deafness in different populations. In the... Ver mais

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Analysis of plant LTR-retrotransposons at the fine-scale family level reveals individual molecular patterns
12.

Analysis of plant LTR-retrotransposons at the fine-scale family level reveals individual molecular patterns

ARTIGO - Inglês

Assunto: Cana-de-açúcar

Background: Sugarcane is an important crop worldwide for sugar production and increasingly, as a renewable energy source. Modern cultivars have... Ver mais

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Analysis of three sugarcane homo/homeologous regions suggests independent polyploidization events of Saccharum officinarum and Saccharum spontaneum
13.

Analysis of three sugarcane homo/homeologous regions suggests independent polyploidization events of Saccharum officinarum and Saccharum spontaneum

ARTIGO - Inglês

Assunto: Cana-de-açúcar

Whole genome duplication has played an important role in plant evolution and diversification. Sugarcane is an important crop with a complex hybrid... Ver mais

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Ancient DNA sequence revealed by error-correcting codes
14.

Ancient DNA sequence revealed by error-correcting codes

ARTIGO - Inglês

Assunto: DNA

A previously described DNA sequence generator algorithm (DNA-SGA) using error-correcting codes has been employed as a computational tool to address... Ver mais

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Androgens by immunoassay and mass spectrometry in children with 46,XY disorder of sex development
15.

Androgens by immunoassay and mass spectrometry in children with 46,XY disorder of sex development

ARTIGO - Inglês

Assunto: Testículos

Steroid measurement is a challenge in pediatric endocrinology. Currently, liquid chromatography with tandem mass spectrometry (LC-MS/MS) is considered... Ver mais

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A new compound heterozygosis for inactivating mutations in the glucokinase gene as cause of permanent neonatal diabetes mellitus (PNDM) in double-first cousins
16.

A new compound heterozygosis for inactivating mutations in the glucokinase gene as cause of permanent neonatal diabetes mellitus (PNDM) in double-first cousins

ARTIGO - Inglês

Assunto: Diabetes Mellitus neonatal permanente

Background: Permanent neonatal diabetes mellitus (PNDM) is a rare disorder, characterized by uncontrolled hyperglycemia diagnosed during the first 6... Ver mais

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An experimental target-based platform in yeast for screening Plasmodium vivax deoxyhypusine synthase inhibitors
17.

An experimental target-based platform in yeast for screening Plasmodium vivax deoxyhypusine synthase inhibitors

PRE-PRINT - Inglês

Assunto: Antimaláricos

Abstract: The enzyme deoxyhypusine synthase (DHS) catalyzes the first step in the post-translational modification of the eukaryotic translation factor... Ver mais

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Angiogenesis‐related genes in endothelial progenitor cells may be involved in sickle cell stroke
19.

Angiogenesis‐related genes in endothelial progenitor cells may be involved in sickle cell stroke

ARTIGO - Inglês

Assunto: Expressão gênica

The clinical aspects of sickle cell anemia (SCA) are heterogeneous, and different patients may present significantly different clinical... Ver mais

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An open source plant kinase chemogenomics set
20.

An open source plant kinase chemogenomics set

ARTIGO - Inglês

Assunto: Artigo original

Abstract: One hundred twenty-nine protein kinases, selected to represent the diversity of the rice (Oryza sativa) kinome, were cloned and tested for... Ver mais

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A novel bret-based assay to investigate binding and residence time of unmodified ligands to the human lysosomal ion channel trpml1 in intact cells
21.

A novel bret-based assay to investigate binding and residence time of unmodified ligands to the human lysosomal ion channel trpml1 in intact cells

ARTIGO - Inglês

Assunto: Artigo original

Abstract: Here, we report a bioluminescence resonance energy transfer (BRET) assay as a novel way to investigate the binding of unlabeled ligands to... Ver mais

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A novel image-based approach for soybean seed phenotyping using machine learning techniques
23.

A novel image-based approach for soybean seed phenotyping using machine learning techniques

ARTIGO - Inglês

Assunto: Artigo original

Abstract: Soybean is important for protein and oil worldwide, requiring investments in research and production technology, mainly breeding programs,... Ver mais

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Antioxidant enzyme activity in Acidithiobacillus ferrooxidans LR maintained in contact with chalcopyrite
24.

Antioxidant enzyme activity in Acidithiobacillus ferrooxidans LR maintained in contact with chalcopyrite

ARTIGO - Inglês

Assunto: Acidithiobacillus ferrooxidans

The total protein content and activity of the enzymes glutathione reductase (GR), superoxide dismutase (SOD) and thioredoxin reductase (TrxR) were... Ver mais

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