Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/93829
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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.titleHypercalcemia And Multiple Osteolytic Lesions In A Child With Disseminated Paracoccidioidomycosis And Pulmonary Tuberculosispt_BR
dc.contributor.authorTresoldi A.T.pt_BR
dc.contributor.authorPereira R.M.pt_BR
dc.contributor.authorCastro L.C.pt_BR
dc.contributor.authorRigatto S.Z.P.pt_BR
dc.contributor.authorBelangero V.M.S.pt_BR
unicamp.authorTresoldi, A.T., Department of Pediatrics, School of Medical Sciences, Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazil, Rua José Paulino, 1875/43 A, CEP 13013-002 - Campinas, SP, Brazilpt_BR
unicamp.authorPereira, R.M., Department of Pediatrics, School of Medical Sciences, Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazilpt_BR
unicamp.authorCastro, L.C., Department of Pediatrics, School of Medical Sciences, UNICAMP, Campinas, SP, Brazilpt_BR
unicamp.authorRigatto, S.Z.P., Department of Pediatrics, School of Medical Sciences, UNICAMP, Campinas, SP, Brazilpt_BR
unicamp.authorBelangero, V.M.S., Department of Pediatrics, School of Medical Sciences, Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazilpt_BR
dc.description.abstractObjective: To describe the case of a child with paracoccidioido-mycosis who presented hypercalcemia with multiple osteolytic lesions. Description: A 6-year-old boy was admitted with a one-month history of fever and hepatosplenomegaly. On admission, he looked sick, pale, and had disseminated lymphadenopathy and hepatosplenomegaly. The laboratory findings included anemia (hemoglobin = 6.8 g/dl), eosinophilia (1,222/mm 3), thrombocytopenia (102,000/mm 3), and hypoalbumlnemia (serum albumin = 2.2 g/dl). Paracoccidioides brasiliensis was identified in bone marrow examination. In the second week after admission, the patient presented joint pain, poor activity and difficulty in walking. He presented hypercalcemia (maximum value = 14.9 mg%) and reduction in renal function, which lasted for two weeks. On the 42nd day after admission, his chest X-ray showed lytic lesions in clavicle, scapula, ribs, and humerus, with bilateral slipped capital humeral epiphysis. The patient presented nephrocalcinosis and nephrolithiasis, reduction in creatinine clearance and evidence of tubular lesions. At the end of the second month after admission, Mycobacterium tuberculosis was isolated in gastric lavage. The child received treatment for paracoccidioidomycosis and tuberculosis and has not had any sequelae for 3 years. Comments: The development of symptomatic hypercalcemia leading to renal lesion, associated with multiple osteolytic lesions, had never been described in paracoccidioidomycosis. Although pulmonary tuberculosis was diagnosed and could be related to hypercalcemia, the sudden onset of hypercalcemia and its normalization without specific treatment for tuberculosis suggests that bone lysis was the most important factor in the genesis of hypercalcemia. Copyright © 2005 by Sociedade Brasileira de Pediatria.en
dc.relation.ispartofJornal de Pediatriapt_BR
dc.date.issued2005pt_BR
dc.identifier.citationJornal De Pediatria. , v. 81, n. 4, p. 349 - 352, 2005.pt_BR
dc.language.isoenpt_BR
dc.description.volume81pt_BR
dc.description.issuenumber4pt_BR
dc.description.firstpage349pt_BR
dc.description.lastpage352pt_BR
dc.rightsabertopt_BR
dc.sourceScopuspt_BR
dc.identifier.issn217557pt_BR
dc.identifier.doi10.2223/1375pt_BR
dc.identifier.urlhttp://www.scopus.com/inward/record.url?eid=2-s2.0-28244461265&partnerID=40&md5=ac3d90214bc14ebb67b5fe501387aae3pt_BR
dc.date.available2015-06-26T14:09:35Z
dc.date.available2015-11-26T14:09:32Z-
dc.date.accessioned2015-06-26T14:09:35Z
dc.date.accessioned2015-11-26T14:09:32Z-
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dc.description.provenanceMade available in DSpace on 2015-11-26T14:09:32Z (GMT). No. of bitstreams: 2 2-s2.0-28244461265.pdf: 311565 bytes, checksum: c1682d01d7a15dab7410be9e401c5fd8 (MD5) 2-s2.0-28244461265.pdf.txt: 21177 bytes, checksum: edbb68b6a950cdfc7bc6c7e0f0b15b0a (MD5) Previous issue date: 2005en
dc.identifier.urihttp://www.repositorio.unicamp.br/handle/REPOSIP/93829
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/93829-
dc.identifier.idScopus2-s2.0-28244461265pt_BR
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