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Type: Artigo de periódico
Title: Chloroquine: Modes Of Action Of An Undervalued Drug
Author: Thome R.
Lopes S.C.P.
Costa F.T.M.
Verinaud L.
Abstract: For more than two decades, chloroquine (CQ) was largely and deliberately used as first choice drug for malaria treatment. However, worldwide increasing cases of resistant strains of Plasmodium have hampered its use. Nevertheless, CQ has recently been tested as adjunct therapy in several inflammatory situations, such as rheumatoid arthritis and transplantation procedures, presenting intriguing and promising results. In this review, we discuss recent findings and CQ mechanisms of action vis-à-vis its use as a broad adjunct therapy. © 2013 Elsevier B.V.
Citation: Immunology Letters. , v. 153, n. 1/Fev, p. 50 - 57, 2013.
Rights: fechado
Identifier DOI: 10.1016/j.imlet.2013.07.004
Date Issue: 2013
Appears in Collections:Unicamp - Artigos e Outros Documentos

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