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dc.contributor.CRUESPUniversidade Estadual de Campinaspt_BR
dc.typeArtigo de periódicopt_BR
dc.titleMultimodal neuroimaging: Potential biomarkers for response to antiepileptic drugs?pt_BR
dc.contributor.authorCoan, ACpt_BR
dc.contributor.authorCendes, Fpt_BR
unicamp.author.emailfcendes@unicamp.brpt_BR
unicamp.authorCoan, Ana C. Cendes, Fernando Univ Estadual Campinas, Dept Neurol, Neuroimaging Lab, BR-13083970 Campinas, SP, Brazilpt_BR
dc.subjectAntiepileptic drugspt_BR
dc.subjectMagnetic resonance imagingpt_BR
dc.subjectFunctional imagingpt_BR
dc.subjectSeizurespt_BR
dc.subjectOutcomept_BR
dc.subjectEpileptogenic lesionspt_BR
dc.subjectNeuronal damagept_BR
dc.subjectBiomarkerspt_BR
dc.subject.wosTemporal-lobe Epilepsypt_BR
dc.subject.wosSeizurept_BR
dc.subject.wosPatternspt_BR
dc.subject.wosAtrophypt_BR
dc.subject.wosMript_BR
dc.description.abstractNeuroimaging techniques in epilepsy are used widely for definition of the epileptogenic lesion and surgical decision. However, its applications extend to the knowledge of epileptic mechanisms and include the identification of prognostic features that can help our decisions on the appropriate type of treatment on an individual basis. Structural neuroimaging may be able to identify patients more likely to respond to antiepileptic drug (AED) treatment and also patients who are better candidates for earlier surgical treatment. In the past decades, quantitative analyses have also improved our knowledge about epileptogenic lesions and networks as well as the following prognoses: seizure control, cognitive outcome, and comorbidities. New advanced neuroimaging techniques such as functional magnetic resonance imaging (MRI) and the development biotracers that could be associated with inflammation and specific genetic patterns will add further knowledge to the development of epilepsy treatments.pt
dc.relation.ispartofEpilepsiapt_BR
dc.relation.ispartofabbreviationEpilepsiapt_BR
dc.publisher.cityHobokenpt_BR
dc.publisher.countryEUApt_BR
dc.publisherWiley-blackwellpt_BR
dc.date.issued2013pt_BR
dc.date.monthofcirculationMAYpt_BR
dc.identifier.citationEpilepsia. Wiley-blackwell, v. 54, n. 67, n. 70, 2013.pt_BR
dc.language.isoenpt_BR
dc.description.volume54pt_BR
dc.description.issuesupplement2pt_BR
dc.description.issuespecialSIpt_BR
dc.description.firstpage67pt_BR
dc.description.lastpage70pt_BR
dc.rightsfechadopt_BR
dc.rights.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.htmlpt_BR
dc.sourceWeb of Sciencept_BR
dc.identifier.issn0013-9580pt_BR
dc.identifier.wosidWOS:000318442300015pt_BR
dc.identifier.doi10.1111/epi.12188pt_BR
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.description.sponsorship1Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.date.available2014-08-01T18:41:15Z
dc.date.available2015-11-26T17:06:14Z-
dc.date.accessioned2014-08-01T18:41:15Z
dc.date.accessioned2015-11-26T17:06:14Z-
dc.description.provenanceMade available in DSpace on 2014-08-01T18:41:15Z (GMT). No. of bitstreams: 0 Previous issue date: 2013en
dc.description.provenanceMade available in DSpace on 2015-11-26T17:06:14Z (GMT). No. of bitstreams: 0 Previous issue date: 2013en
dc.identifier.urihttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/82164
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/82164-
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