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|Type:||Artigo de periódico|
|Title:||Leucotrichoic acid, a novel sesquiterpene from Sinningia leucotricha (Gesneriaceae)|
de Sa, EL
|Abstract:||Chemical investigation of Sinningia leucotricha (Gesneriaceae) resulted in the isolation of leucotrichoic acid, a sesquiterpene with a novel triquinane skeleton, and the known triterpenes hederagenin and 23-hydroxyursolic acid. The chemical structures of all compounds were elucidated through spectroscopic analysis (NMR and MS). The conformational stability of the new compound was analyzed by density theory functional methods. A possible biogenesis for the new compound is proposed. Leucotrichoic acid was inactive against a panel of human cancer cell lines. (C) 2013 Elsevier Ltd. All rights reserved.|
|Editor:||Pergamon-elsevier Science Ltd|
|Citation:||Tetrahedron Letters. Pergamon-elsevier Science Ltd, v. 54, n. 35, n. 4735, n. 4737, 2013.|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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