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dc.contributor.CRUESPUniversidade Estadual de Campinaspt_BR
dc.typeArtigo de periódicopt_BR
dc.titleTumor Growth Characteristics of the Walker 256 AR Tumor, a Regressive Variant of the Rat Walker 256 A tumorpt_BR
dc.contributor.authorGuimaraes, Fpt_BR
dc.contributor.authorSchanoski, ASpt_BR
dc.contributor.authorCavalcanti, TCSpt_BR
dc.contributor.authorJuliano, PBpt_BR
dc.contributor.authorViera-Matos, ANpt_BR
dc.contributor.authorRettori, Opt_BR
unicamp.author.emailsamico@caism.unicamp.brpt_BR
unicamp.authorGuimaraes, Fernando Schanoski, Alessandra Soares Samico Cavalcanti, Tereza Cristina Juliano, Priscila Bianchi Viera-Matos, Ana Neuza Rettori, Ovidio Univ Estadual Campinas, Labs Clin Especializados, BR-13083970 Campinas, SP, Brazilpt_BR
dc.subjectTumor growth ratept_BR
dc.subjectspontaneous tumor regressionpt_BR
dc.subjectWistar ratspt_BR
dc.subjectWalker 256pt_BR
dc.subject.wosCarcinomapt_BR
dc.subject.wosExpressionpt_BR
dc.subject.wosBearingpt_BR
dc.subject.wosImmunosurveillancept_BR
dc.subject.wosResponsespt_BR
dc.subject.wosImmunitypt_BR
dc.subject.wosEscapept_BR
dc.subject.wosAnemiapt_BR
dc.description.abstractThe present study aimed at characterizing the subcutaneous development of the Walker 256 (W256) AR tumor, a regressive variant of the rat W256 A tumor. Wistar rats were injected subcutaneously with 4x10(6) W256 A or W256 AR tumor cells. The development of tumors was evaluated daily by percutaneous measurements. None of the W256 A tumors (n=20) regressed, but 62% of the W256 AR tumor-bearing rats (n=21) underwent complete tumor regression within 35 days. Continuous growth of AR tumors was characterized by an increase of the tumor growth rate from day 12, which reached values above 1.0 g/day, and were significantly higher (p<0.05) than those of the regressive AR tumors. Immunosuppression by irradiation before subcutaneous injection of AR cells completely abrogated tumor regression and was associated with severe metastatic dissemination. Daily evaluation of the tumor growth rate enabled the discrimination, in advance, between continuously growing tumors and those that regressed later on.pt
dc.relation.ispartofBrazilian Archives Of Biology And Technologypt_BR
dc.relation.ispartofabbreviationBraz. Arch. Biol. Technol.pt_BR
dc.publisher.cityCuritiba-paranapt_BR
dc.publisher.countryBrasilpt_BR
dc.publisherInst Tecnologia Paranapt_BR
dc.date.issued2010pt_BR
dc.date.monthofcirculationSEP-OCTpt_BR
dc.identifier.citationBrazilian Archives Of Biology And Technology. Inst Tecnologia Parana, v. 53, n. 5, n. 1101, n. 1108, 2010.pt_BR
dc.language.isoenpt_BR
dc.description.volume53pt_BR
dc.description.issuenumber5pt_BR
dc.description.firstpage1101pt_BR
dc.description.lastpage1108pt_BR
dc.rightsabertopt_BR
dc.sourceWeb of Sciencept_BR
dc.identifier.issn1516-8913pt_BR
dc.identifier.wosidWOS:000284591200014pt_BR
dc.identifier.doi10.1590/S1516-89132010000500014pt_BR
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)pt_BR
dc.description.sponsorshipCAISM/UNICAMPpt_BR
dc.description.sponsorship1Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)pt_BR
dc.description.sponsordocumentnumberCAPES [2067-030]pt
dc.date.available2014-11-14T06:46:07Z
dc.date.available2015-11-26T17:13:43Z-
dc.date.accessioned2014-11-14T06:46:07Z
dc.date.accessioned2015-11-26T17:13:43Z-
dc.description.provenanceMade available in DSpace on 2014-11-14T06:46:07Z (GMT). No. of bitstreams: 1 WOS000284591200014.pdf: 433860 bytes, checksum: 2451c8bb7b532ecadbf3e200c97eceec (MD5) Previous issue date: 2010en
dc.description.provenanceMade available in DSpace on 2015-11-26T17:13:43Z (GMT). No. of bitstreams: 2 WOS000284591200014.pdf: 433860 bytes, checksum: 2451c8bb7b532ecadbf3e200c97eceec (MD5) WOS000284591200014.pdf.txt: 30706 bytes, checksum: 701cca5292d24d82021d6602a58030de (MD5) Previous issue date: 2010en
dc.identifier.urihttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/77061pt_BR
dc.identifier.urihttp://www.repositorio.unicamp.br/handle/REPOSIP/77061
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/77061-
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