Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/74000
Full metadata record
DC FieldValueLanguage
dc.contributor.CRUESPUniversidade Estadual de Campinaspt_BR
dc.typeArtigo de periódicopt_BR
dc.titleSyndecan-1 (CD138) and Ki-67 expression in different subtypes of ameloblastomaspt_BR
dc.contributor.authorBologna-Molina, Rpt_BR
dc.contributor.authorMosqueda-Taylor, Apt_BR
dc.contributor.authorLopez-Corella, Ept_BR
dc.contributor.authorAlmeida, OPpt_BR
dc.contributor.authorCarrasco-Daza, Dpt_BR
dc.contributor.authorGarcia-Vazquez, Fpt_BR
dc.contributor.authorFarfan-Morales, JEpt_BR
dc.contributor.authorIrigoyen-Camacho, MEpt_BR
dc.contributor.authorDamian-Matsumura, Ppt_BR
unicamp.author.emailrbologna@correo.xoc.uam.mxpt_BR
unicamp.authorBologna-Molina, R. Univ Autonoma Metropolitana, Mexico City, DF, Mexicopt_BR
unicamp.authorMosqueda-Taylor, A. Irigoyen-Camacho, M. E. Univ Autonoma Metropolitana Xochimilco, Hlth Care Dept, Mexico City, DF, Mexicopt_BR
unicamp.authorLopez-Corella, E. Carrasco-Daza, D. Garcia-Vazquez, F. Farfan-Morales, J. E. Inst Nacl Pediat, Lab Mol Pathol, Mexico City, DF, Mexicopt_BR
unicamp.authorAlmeida, O. P. Univ Estadual Campinas, Sch Dent Piracicaba, Oral Pathol Sect, Dept Oral Diag, Piracicaba, SP, Brazilpt_BR
unicamp.authorDamian-Matsumura, P. Univ Autonoma Metropolitana Iztapalapa, Dept Reprod Biol, Mexico City 09340, DF, Mexicopt_BR
dc.subjectameloblastomapt_BR
dc.subjectodontogenic tumorspt_BR
dc.subjectsyndecan-1pt_BR
dc.subjectCD138pt_BR
dc.subjectKi-67pt_BR
dc.subject.wosCell Nuclear Antigenpt_BR
dc.subject.wosHeparan-sulfate Proteoglycanspt_BR
dc.subject.wosSurface Proteoglycanpt_BR
dc.subject.wosUnicystic Ameloblastomapt_BR
dc.subject.wosPrognostic-significancept_BR
dc.subject.wosCystic Ameloblastomapt_BR
dc.subject.wosLung-carcinomapt_BR
dc.subject.wosGrowth-factorpt_BR
dc.subject.wosCancerpt_BR
dc.subject.wosAssociationpt_BR
dc.description.abstractAmeloblastoma is the most frequent odontogenic tumor and is considered a benign, but locally invasive, neoplasm with variable clinico-pathological expression. Syndecan-1 is a cell surface proteoglycan that binds cells to the extracellular matrix and its expression is down-regulated in many cellular transformation models. The aims of this study were to examine the pattern of syndecan-1 expression, to evaluate the proliferating activity in a large series of solid/multicystic (SA) and unicystic ameloblastomas (UA), and to study its possible correlation to their biological behavior. Immunohistochemical studies were performed for syndecan-1 (clone MI15) and Ki-67 (cloneMIB-1) in 120 ameloblastomas (75 SA and 45 UA). The salient finding was that expression of syndecan-1 was related to the histological. subtype of tumors, as there was a lower expression in SA (40.2%) as compared to UA (49.7%) (p < 0.05). These findings did not correlate with Ki-67 expression, as this was similar in both types of ameloblastomas. Our results suggest that the reduced expression of syndecan-1 supports the view that SA has a more aggressive biological. behavior than the UA. The lack of correlation between reduction of the syndecan-1 and Ki-67 index may be due to the different histomorphologies of both types of ameloblastoma, and more studies are necessary to better understand the role of this protein in the biological behavior of these tumors. (c) 2007 Elsevier Ltd. All rights reserved.pt
dc.relation.ispartofOral Oncologypt_BR
dc.relation.ispartofabbreviationOral Oncol.pt_BR
dc.publisher.cityAmsterdampt_BR
dc.publisher.countryHolandapt_BR
dc.publisherElsevier Science Bvpt_BR
dc.date.issued2008pt_BR
dc.date.monthofcirculationAUGpt_BR
dc.identifier.citationOral Oncology. Elsevier Science Bv, v. 44, n. 8, n. 805, n. 811, 2008.pt_BR
dc.language.isoenpt_BR
dc.description.volume44pt_BR
dc.description.issuenumber8pt_BR
dc.description.firstpage805pt_BR
dc.description.lastpage811pt_BR
dc.rightsfechadopt_BR
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policypt_BR
dc.sourceWeb of Sciencept_BR
dc.identifier.issn1368-8375pt_BR
dc.identifier.wosidWOS:000258649500012pt_BR
dc.identifier.doi10.1016/j.oraloncotogy.2007.10.007pt_BR
dc.date.available2014-11-19T13:48:32Z
dc.date.available2015-11-26T18:03:38Z-
dc.date.accessioned2014-11-19T13:48:32Z
dc.date.accessioned2015-11-26T18:03:38Z-
dc.description.provenanceMade available in DSpace on 2014-11-19T13:48:32Z (GMT). No. of bitstreams: 1 WOS000258649500012.pdf: 1834417 bytes, checksum: 5a422d9bf02117a5a7368c625c160e62 (MD5) Previous issue date: 2008en
dc.description.provenanceMade available in DSpace on 2015-11-26T18:03:38Z (GMT). No. of bitstreams: 2 WOS000258649500012.pdf: 1834417 bytes, checksum: 5a422d9bf02117a5a7368c625c160e62 (MD5) WOS000258649500012.pdf.txt: 28719 bytes, checksum: e8f6437f5916ec7b68a438ac3f671d1b (MD5) Previous issue date: 2008en
dc.identifier.urihttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/74000pt_BR
dc.identifier.urihttp://www.repositorio.unicamp.br/handle/REPOSIP/74000
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/74000-
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
WOS000258649500012.pdf1.79 MBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.