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Type: Artigo de periódico
Title: Effect of goniothalamin on the development of Ehrlich solid tumor in mice
Author: Vendramini-Costa, DB
de Castro, IBD
Ruiz, ALTG
Marquissolo, C
Pilli, RA
de Carvalho, JE
Abstract: In this work the antiproliferative activity of goniothalamin (1), both in racemic and in its enantiomeric pure forms, in a solid tumor experimental model using laboratory animals is described. The antiedematogenic activity displayed by racemic 1 in the carrageenan edema model in mice together with the reduction of Ehrlich solid tumor model suggest a relationship between anticancer and antiinflammatory activities with the antiinflammatory activity favoring the antiproliferative activity itself. (c) 2010 Elsevier Ltd. All rights reserved.
Subject: Goniothalamin
Ehrlich solid tumor
Country: Inglaterra
Editor: Pergamon-elsevier Science Ltd
Citation: Bioorganic & Medicinal Chemistry. Pergamon-elsevier Science Ltd, v. 18, n. 18, n. 6742, n. 6747, 2010.
Rights: fechado
Identifier DOI: 10.1016/j.bmc.2010.07.053
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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