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Type: Artigo de periódico
Title: Phenylpropanoid glucosides from leaves of Coussarea hydrangeifolia (Rubiaceae)
Author: Hamerski, L
Bomm, MD
Silva, DHS
Young, MCM
Furlan, M
Eberlin, MN
Castro-Gamboa, I
Cavalheiro, AJ
Bolzani, VD
Abstract: Phenylpropanoid glycosides, 1 '-O-benzyl-alpha-(L)-rhamnopyranosyl-(1 ''-> 6 ')-beta-(D)-glucopyranoside (1) and alpha-(L)-Xylopyranosyl(4 '', 2 ')-(3-O-beta-(D)-glucopyranosyl)-1 '-O-E-caffeoyl-beta-(D)-glucopyranoside (2), together with the known derivatives, 1,6-di-O-caffeoyl- beta-(D)-glucopyrano side (3), 1-O-(E)-caffeoyl-beta-(D)-glucopyranoside (4) and 1-O-(E)-feruloyl-beta-(D)-glucopyranoside (5), were isolated from leaves of Coussarea hydrangeifolia. Their structures were determined by IR, HRESIMS, and I D and 2D NMR experiments, and their antioxidant activities, evaluated by assaying the free radical scavenging capacity using the DPPH (1,1-diphenyl-2-picrylhydrazyl) radical as substrate. The antioxidant activities of 3 and 4 (IC50 values of 15.0 and 19.2 mu M, respectively) were comparable to that of the standard positive control caffeic acid, whilst 2 and 5 were only weakly active and 1 was inactive. (c) 2005 Elsevier Ltd. All rights reserved.
Subject: Coussarea hydrangeifolia
phenylpropanoid glycosides
antioxidant activity
Country: Inglaterra
Editor: Pergamon-elsevier Science Ltd
Citation: Phytochemistry. Pergamon-elsevier Science Ltd, v. 66, n. 16, n. 1927, n. 1932, 2005.
Rights: fechado
Identifier DOI: 10.1016/j.phytochem.2005.06.019
Date Issue: 2005
Appears in Collections:Unicamp - Artigos e Outros Documentos

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