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Type: Artigo de periódico
Title: Proteome analysis of lumbar spinal cord from rats submitted to peripheral lesion during neonatal period
Author: Castro-Dias, E
Vieira, AS
Werneck, CC
Langone, F
Novello, JC
Martins-de-Souza, D
Abstract: Every year traumatic peripheral nerve injuries (TPNI) result in considerable physical disability across the world; the mechanisms of plasticity and reorganization of spinal cord circuits following such injuries are complex and not completely understood. A comparative proteome analysis between neonatal rats submitted to peripheral lesion and controls was performed; a number of differentially expressed proteins involved in oxidative stress response, energy metabolism and cytoskeleton rearrangement were revealed, which may support future studies to help in the understanding and a posteriori the treatment of TPNI.
Subject: Proteome
Spinal cord
Nerve injury
Country: Austria
Editor: Springer Wien
Citation: Journal Of Neural Transmission. Springer Wien, v. 117, n. 6, n. 689, n. 693, 2010.
Rights: fechado
Identifier DOI: 10.1007/s00702-010-0403-x
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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